Lecture 5

Question 1

What is CRISPR/Cas9?

Question 1

How can genome editing be used to correct genetic diseases?

Question 2

Compare and contrast the 3 basic cytoskeleton components and the key features of the polymer structures they form.

Question 3

Discuss the dynamic nature of the cytoskeleton in terms of microtubule “dynamic instability.”

Question 4

Explain the role of microtubules in cell division, intracellular transport, and flagella/cilia.

Question 5

Describe the roles of intermediate filaments. How are they similar or different to microfilaments and microtubules?

Question 6

Discuss the cytoskeletal dysfunctions that were presented in class and the associated disease states/

Question 7

Broadly outline the 3 different forms of intracellular transport we discussed.

Question 8

Explain how proteins undergo transmembrane transport to enter the ER.

Question 9

How are proteins properly folded and sorted from this site? How is this relevant for cystic fibrosis?

Question 10

Describe the process of vesicle transport.