lecture 3: pharmocology orientation Flashcards
beta blockers end in
“lol”
alpha blockers end in
“sin”
ACE inihibitors end in
“pril”
Calcium channel blockers end in
“pine”
diuretic agents end in
“ide”
what are some things that could effect drugs concentration at site of action?
- physio variables
- pathological factors
- genetic factors
- interaction with other drugs
- development of tolerance
- desensitization
functional antagonist
2 agonists interact with different receptors to produce opposite effects
chemical antagonist
Drug counters the effect of another resulting in decreased effect.
dispositional antagonist
Metabolism of a chemical is altered and the concentration and/or duration of the chemical are diminished.
receptor antagonist
receptor configuration/specificity
Therapeutic Equivalence
Must be pharmaceutically-equivalent AND expected to have the same…
- Therapeutic (clinical) effect
- Safety profile
Bioequivalence
- Similar rate & extent of absorption
2. 80% -125% of reference product
how many pounds does 1 Kg equal?
2.2 pds
schedule 1 drugs
-All non-research use illegal under federal law.
No currently accepted medical use and a high potential for abuse. Ex: Flunitrazepam(Rohypnol), Marijuana, LSD, PCP
schedule 2 drugs
-No telephone Rx’s, no refills
Drugs with a high potential for abuse, with use potentially leading to severe psychological or physical dependence. Ex: Opioids, Cannabinoids, Amphetamines, Phenobarbital
