Lecture 3 - Overview of exercise metabolism Flashcards
What are the ATP dependent processses in skeletal muscle
Cross-bridge cycling (myosin ATPase) - takes up the most energy
Sarcolemmal excitablity (Na+ / K+ ATPase) - depolarising and re-polarising
Calcium pumping into SR (SERCA - Ca2+ ATPase)
Fatigue is often related to disturbances of the..
Na+ K+ balance
because muscle is about 70% water there’s about a 4-fold increase in concentration when it’s reported as
wet , as opposed to dry
many of the metablic pathways are sensitive to…
the level of ATP
If you inject ATP into muscle what happens?
the metabolic pathways are deactivated
ATP levels are the regulating variable - if depleted, you turn on the metabolic pathways
Fats can only be…
oxidised
Protein is only used in the oxidative metabolism when the subject is
Exercising ALOT or starving
PCr + ADP + H+ –>
ATP + creatine
2ADP —>
ATP + AMP
Glycogen + 3ADP + 3P(i) —>
2 Lactic acid + H+ + 3ATP
What is the power of the energy systems?
The rate of generating ATP
The power of the system is inversely related to the ..
capacity of the system - how long it can sustain ATP production
The energy systems used at onset of exercise are
PCr and Glycolysis
The heavier the weight lifted in resistance training, the more likely you will
occlude the oxygen supply by compresssing the capillaries
will start to rely of Creatine phosphate and other anaerobic substrates
In aerobic exercise the oxygen uptake is linearly related to the …
power output / exercise intensity
once gone above the maximum, need to start using anaerobic systems