Lecture 17 - Physiological determinants of exercise performance Flashcards

1
Q

What are the potential sites of fatigue?

A

Excitatory input to motor cortex

excitatory drive to lower motoneuron

motoneuron excitabililty

NM junction

sarcolemma excitability

excitation- contraction coupling

contractile mechanism

metabolic energy supply

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2
Q

Feedback from the muscle to the brain can modify the central motor drive

when the feedback is inhibited, what happens?

A

the muscle initially has a larger power output, but will fatigue quicker and reduce power output below that of subjects without the inhibition

There’s normally a balance between how much the CNS wants to drive the muscle and how much the muscle is actually coping

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3
Q

What are the potential factors or fatigue?

A

Central fatigue

Ionic disturbances

Impaired excitation- contraction coupling

Substrate depletion (ATP, PCr, CHO)

Metabolite accumulation (Pi, H+, ROS)

Fluid and electrolyte loss

Hyperthermia

Muscle damage

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4
Q

What are the essential factors for sprint success?

A

Muscle mass to geerate force and pwoer

Fast twitch fibres

Neuromusclar recruitment

fatigue resistance

Ability to generate and tolerate lactic acid (buffer capacity)

Fast reaction time

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5
Q

What are the essential factors for sprint success?

A

Muscle mass to generate force and power

Fast twitch fibres

Neuromuscular recruitment

fatigue resistance

Ability to generate and tolerate lactic acid (buffer capacity)

Fast reaction time

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6
Q

intermittent activity that involve high intensity efforts and periods of rest will be influenced by ____ availability

When more ___ is available, the output for each bout of exercise will decrease to a lesser extent

A

glycogen

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7
Q

What is the rationale for increasing extra-celullar pH?

A

A decrese in the msucle pH is associated with fatigue

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8
Q

What are the essential elements for endurance success?

A

High VO2 max - a big engine, and this is how it’s defined

Ability to maintain high % of VO2 max (fractional utilisation)

High power output at lactate threshold - muscle oxidative capacity

fatigue resistance

efficient/economical technique

Ability to oxidise fat at high power outputs

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9
Q

As cyclists get better what happens to the way muscles are used in the lower limb

A

the load is spread around so it’s not just the quadriceps providing the power output.

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10
Q

elite cyclists will have a steadily high VO2 max but the muscle oxidative capacity will…

A

vary depending on whether it’s off-season, will go down a bit

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11
Q

The increase is muscle oxidative capacity means that you don’t use as much ___

A

glycogen

in other words for the same level of glycogen use, you can exercise at a higher intensity

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12
Q

It is not only the amount of muscle glycogen, but also…

A

where exactly it is which is relevant

some needed around the sacroplasmic reticulum for Ca2+ channels for instance (checkthat)

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13
Q

Glycogen loading works well for events longer than…

A

90 mins

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14
Q

Carbohydrate ingestion improves…

A

exercise capacity

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15
Q

How does Carbohydrate ingestion improve performace?

A

Prevents fall in glucose

maintain mscle CHO oxidation and brain glucose supply

reduces perception of fatigue

Increases exercise time to fatigue and power output

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16
Q

Fluid and CHO ingestion ____ improve performance

A

independently

they are independent and additive

17
Q

VO2 max is about __% heritable

A

50%

half trainable, half genetics

18
Q

What are the strategies to enhance fatigue resistance?

A

Training - physical, technical, metal

Nutrition - CHO, fluid, protein

Heat acclimatisation / cooling

Drugs / Supplements / gene doping