Lecture 3--Membrane Potentials Flashcards
T/F: The plasma membrane is electrically polarized
True
The voltage difference across the cell membrane
Membrane Potential (Vm)
Cells use ___ as a battery and for signaling purposed
membrane potential
Membrane Potential (Vm) is proportional to:
separation of positive and neg ions (sep of charge across membrane)
____ acts as a capacitor and stores charge
cell membrane
Several factors influence distribution of ions across cell membrane:
1) active transport of the ion
2) conc gradient
3) volatge gradient
4) conductance of ion across membrane
Conductance of the ion across the membrane is determined by:
1) number of channels aka permeability
2) simple diffusion
Ion diffusio is determijed by the
E/C Gradient
The concentration difference for K+ across membrane is roughly balanced by the intracellular negative charge created by ___
–efflux due to:
–influx due to:
impermeant anions
efflux: conc grad
influx: elect grad
The electrical potential that counters net diffusion of K+ is ____
K+ equilibrium potential (Ek)
What 2 things need to be considered when determining the effect of an ion on the membrane potential?
1) concentration gradient
2) permeability
(nernst eq assumes membrane is 100% perm to said ion)
Equation including permeability of all ions contributing to membrane potential
Goldman Constant Field Equation