Lecture 3 ( Lipids ) Flashcards

1
Q

Main three categories of Lipids

A

Simple lipids, Compound Lipids and Derived lipids

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2
Q

Monocarboxylic Acids Containing Even number of carbon atoms

A

Fatty Acids

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3
Q

Simple Lipids are made of

A

Fatty acid + alcohol (esters)

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4
Q

Compund Lipids are made of

A

Fatty acids + Alcohol + Other Group ( Simple lipid + other group)

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5
Q

A category of lipids which can be obtained from the hydrolysis of the other two

A

Derived Lipids

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6
Q

Mention the three types of identifying a carbon in the fatty acids and mention direction of numbering

A

1) 1 ,2,3,4 From the carboxylic group
2) alpha , beta , gamma , delta , epsilon from the carboxylic group
3) omega 1, omega 2, omega 3 ,…. from the methyl group

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7
Q

classification of the faty acids accordinig to bonds is either …. or ….

A

Saturated or Unsaturated

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8
Q

Unsaturated fatty acids are ( and mention the subcategories )

A

Fatty acids which has double bonds.
1. if it has only one then it’s called “Monoenoic (AKA monoethenoid)”
2. if it has more than one then it’s called polyenoic (PUFA)

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9
Q

The two families in the PUFA subcategory is

A

w3 and w6

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10
Q

The most Important SFA (Saturated Fatty acids) and mention it’s importance

A

palmatic acid
The most common in human tissues and produces TAG (Triacylglycerols)

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11
Q

Bio Medical Hazards of SFA

A

As it includes saturated fatty acids, it increases the cholestrol level which results in coronary heart diseases

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12
Q

Importance of Monoenoic Acids

A

Monoeic acid decreases plasma cholestrol

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13
Q

Importance of W6

A

Decrease Plasma cholestrol

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14
Q

importance of w3 (4 points)

A

1) Decrease Cholestrol which prevents Cardiovascular diseases
2) lower the blood pressure
3) lower triacylglycerol levels
4) lower the tendency of thrombosis

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15
Q

Nutritional Classification of F.A. (2 categories )

A

1) Essential ( not synthesized in body ) (essential in diet)
2) Non - Essential
Synthesized in body and not essential in diet

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16
Q

Examples of each nutirtional fatty acids

A

1) Essential
alpha lenolenic w3
lenoleic w6
2) Non Essential
any other fatty acids

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17
Q

Simple Lipids are either

A

1) Neutral Fats (TAGs )
2) Waxes

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18
Q

TAG is made of

A

3 fatty acids with glycerol

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19
Q

Waxes are made of

A

1 fatty acids with long chain monohydroxyl alcohol higher than glycerol

20
Q

Examples of conjugated lipids

A

Phospholipids
Glycolipids

21
Q

2 Examples of Phospholipids

A

Glycerophospholipids
Sphingomyelin

22
Q

Alcohol in Glycerophosphlipids

23
Q

Alcohol in sphingomyelin

A

Sphingosine

24
Q

Importance of Phospholipids ( 4 Points )

A
  1. Help digestion and absorbtion of Fats (emulsifying factor )
  2. Important constituent of cell membrane (Lipid bilayer )
  3. Important constituent of plasma lipoprotein (lipid and proiein ) soluble in water
  4. Amphipathic molecules
25
Main Components of Glycolipids
Shingosine, Fatty acid and CHO
26
Glycolipids is present in
Nervous tissue and RBCs
27
Examples of glycolipids
Cerebroside , Gangliosides
28
Derived lipids resulted from hydrolysis
Fatty acid Alcohols
29
Derived lipids which are associated with lipids
Steroids Cartenoids Vitamins ( K, E, D, A )
30
Steroids is composed of (structure)
4 rings with 17 carbon atoms
31
Types of steroids
Sterols Bile acids Steroid Hormones
32
The most important animal sterol
Cholestrol
33
Cholestrol is present in
All tissues but in higher concentration in brain , nervous tissue , liver , adrenals , gonads,, skin and adipose tissue
34
precursor of cholestrol
Active acetate
35
Normal level of cholestrol in blood
120-200 mg/dl
36
Importance and derivatives of cholestrol
1. Converted to bile acids and bile salts in liver 2. Precursor of steroid hormones 3. Source of vitamin D3
37
Hazards of cholestrol and mention the level
>200 mg/dl results in arthrosderosis and coronary heart disease
38
Importance of Bile Acids
1. Removes excessive Cholestrol by converting them to bile salts (bile salts is responsible for emulsification) 2. Help in digestion and absorption of Fats
39
Two categories of steroid hormones
1. Sex Hormones 2. Corticoids
40
Male Sex hormone
Testesterone
41
Female sex hormones
Estrogen: Estradol progesterone
42
Corticoids subcategories and their most important example
Glucocorticoides ( Cortisol ) Mineral corticoides (aldosterone)
43
This vitamin is essential for blood clotting and healthy bones. Without it, you would bleed excessively from a minor cut
Vitamin K
44
This vitamin is a powerful antioxidant that helps protect your cells from damage
Vitamin E
45
Known as the “sunshine vitamin,” your body creates it from exposure to sunlight. It’s important for bone and muscle health and can help protect you from osteoporosis
Vitamin D
46