Lecture 3 Integument - changes that affect the skin Flashcards
The best way to prevent skin wrinkles is to _
Avoid exposure to ultraviolet light.
Functions of the skin
- Thermoregulation.
- Excretion of metabolic wastes.
- Protection of underlying structures.
- Synthesis of vitamin D.
- Maintenance of fluid and electrolyte balance.
- Sensation of pain, touch, pressure, temperature, and vibration.
Age-related changes that may impact skin wellness
- ↓ epidermal proliferation.
- Thinner dermis, flattened dermal-epidermal junction.
- ↓ moisture content.
- ↓ sweat and sebaceous glands.
Epidermis
The relatively impermeable outer layer of skin that serves as a barrier, preventing both the loss of body fluids and entry of substances from the environment.
Langerhans cells
- Antigen-presenting immune cells in the epidermis that serve as macrophages and thus prevent infection.
- Decrease in quantity with age, particularly in sun-exposed skin (decrease of 50-70% in these areas).
Dermis
The layer of skin beneath the epidermis, made up primarily of collagen and serving the functions of temperature regulation, sensory perception, and nourishment for all skin layers.
Dermal-epidermal junction
- Region between the dermis and epidermis; connected by papillae.
- Flattens with age, slowing the transfer of nutrients and oxygen between the dermis and epidermis.
The _ is the inner layer of fat tissue that protects the underlying tissues from trauma.
Subcutis.
_ sweat glands, which are important for thermoregulation, open directly onto the skin surface and are most abundant on the palms, soles, and forehead.
Eccrine.
_ sweat glands, whose sole function is to produce secretions, open into hair follicles, primarily in the axillae and genital area.
Apocrine.
_ glands continually secrete sebum, which prevents the loss of water and serves as a mild retardant of bacterial and fungal growth.
Sebaceous.
Xerosis
- Dry skin; likely to be exacerbated when relative humidity is below 30%, or as a result of fluid loss from diuretics.
- Found in up to 85% of non-institutionalized older people.
_ agents are the type of drug most commonly associated with hair loss.
Cytotoxic (e.g., methotrexate).
General skin characteristics
- Largest body organ (21 square feet).
- Normally dry, supple, and acidic (pH 4-6) - helps fight bacteria.
- “Brick and mortar” construction (cells are bricks, skin oils are the mortar).
- Proper hydration required for prevention of Trans Epidermal Water Loss (TEWL).
- Total thickness of the epidermis and dermis varies, but averages just over 2 mm.
Flattening of the dermal-epidermal junction places older adults at increased risk for _
Skin tears.
The stratum lucidum is the layer of skin that is found only on _
The palms of the hands and soles of the feet.
Epidermal mitosis is inhibited by the administration of _
Steroids, chemotherapy, and NSAIDs (at high doses).
Older adults tend to have more allergic reactions because the number of _ increases with age.
Mast cells.
The point of origin for a pressure ulcer is _
Where the bone hits the muscle (not on the surface of the skin).