Lecture 3: Functional Property of Neurons Flashcards
To study the electrical properties of neurons they studied the squid giant axon and learned that the motor neuron is responsible for escape response, dissected neuron can survive in sea water for up to 2 days
Hodgkin and Huxley
Neurons at rest have a resting membrane potential between (blank) and (blank) mV
-50 and -80 mV
Work from Neher and Sakmann where they were able to record a single neuron from a single ion channel
Patch Clamp Recording
Continually pushes Na+ ions out and pulls K+ ions in, requires a considerable amount of energy
Sodium Potassium Pump (Na+/K+ pump)
When the interior of the neuron is more negative
Hyperpolarizing
When the interior of the neuron becomes more positive
Depolarizing
The more intense a stimulus is, the faster the neuron will fire, a strong stimulus will cause the neuron to fire much faster than a weak one
The Rate Law
Neuron won’t fire no matter how strong the stimulus, arises because the Na+ channel won’t open again for a short while after being open
Absolute Refractory Period
Stronger Stimulus than normal needed to make the neuron fire, corresponds to the period of hyperpolarization
Relative Refractory Period
What stops an action potential from going in the wrong direction?
The refractory period