Lecture 3 (B) - Liver and spleen Flashcards
What is the liver attached to?
Develops in the ventral mesentery connected the abdominal wall via the falciform ligament and the stomach via the lesser omentum. It is also in direct contact with part of the diaphragm and is mostly under the cover of the rib cage.
What makes the separation of the left and right functional lobes of the liver?
- Falciform ligament
- Gall bladder
- IVC
What marks the separation of the quadrate and caudate lobes?
The porta (which carries the hepatic artery, portal vein, common bile duct and the lymphatics within it)
What are the four lobes of the kidney?
- Right
- Left
- Caudate
- Quadrate
How is blood supplied to the liver?
Via the hepatic artery (highly oxygenated) and the hepatic portal vein coming from the abdominal viscera and spleen (not very well oxygenated but nutrient-rich)
How is blood drained from the liver?
Through three short veins that drain directly into the IVC.
What happens to the portal/systemic blood flow in liver disease?
The portal-systemic anastomoses may become dilated if the portal blood flow through the liver is obstructed.
What forms the ampulla of Vater?
Common bile duct and pancreatic duct, entering the duodenum at the major duodenal papilla.
What controls the movement of pancreatic juice/bile into the duodenum?
Sphincter of Oddi - tonically active so must be relaxed to allow the pancreatic juice to pass through into the duodenum.
What forms the common bile duct?
The common hepatic duct and the cystic duct (from the gall bladder).
How can bile/pancreatic juice flow be obstructed?
In cases of pancreatic neoplasms, tumours can obstruct the ducts and cause pancreatitis, which may lead to the auto-digestion of the pancreatic tissue due to activation of enzymes.
What forms the common hepatic duct?
Left and right hepatic ducts.
What is the spleen?
The largest lymphoid organ in the body - technically not a GI tract organ but its blood flow is similar to that of the GI tract and it drains into the liver via the hepatic portal vein.
Is the spleen within a mesentery?
It is suspended in the dorsal foregut mesentery.
Where is the spleen located?
Lies posteriorly on the left side, under ribs 9, 10 and 11.
What ligaments are part of both the greater omentum and the spleen?
- Gastrosplenic ligament
- Splenorenal ligament