Lecture 3 Flashcards

Circulation to the Brain and Spinal Cord: CSF and Vascular Systems

1
Q

What are the 2 fluid systems in NS?

A

Cerebrospinal fluid (CSF)
Vascular

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2
Q

Where is CSF formed? and where does it flow?

A

Formed: Choroid plexus

Flow: between ventricles & into subarachnoid space and then is absorbed back into venous system

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3
Q

What does CSF help with?

A

nutrients, removing waste products

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4
Q

CSF and meninges provide what function?

A

shock absorption to brain when head is hit

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5
Q

how many ventricles do we have?

A

2 C-shaped lateral ventricles
3rd ventricle
4th ventricle

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6
Q

placement of lateral ventricles: (lateral wall, below/above body)

A

Lateral wall - caudate nucleus
Below body - thalamus
Above body - corpus callosum

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7
Q

Lateral ventricles connect to each other and the 3rd ventricle by

A

Interventricular Foramina (Foramina of Monro)

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8
Q

Where is 3rd ventricle?

A
  • narrow in midline of diencephalon
  • surrounded by thalamus and hypothalamus
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9
Q

what connects 3rd and 4th ventricle through the midbrain?

A

Cerebral aqueduct (aqueduct of Sylvius)

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10
Q

where is the 4th ventricle?

A

posterior to pons/medulla and anterior to cerebellum

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11
Q

Where does the 4th ventricle connect and drain into?

A
  • connects to central canal of SC
  • drains into the subarachnoid space
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12
Q

The 4th ventricle drain into the spinal canal through which pathway?

A

2 lateral foramina (foramina of Luschka/lateral aperture) and midline foramen of Magendie (medial aperture)

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13
Q

What are the 3 meninges?

A
  • Dura mater
  • Arachnoid mater
  • Pia mater
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14
Q

What is the outer and the inner dura mater layer attached to?

A
  • outer layer is firmly attached to inside of skull
  • inner layer is attached to arachnoid
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15
Q

The inner and outer dura mater layers are fused except:

A

at dural sinuses which collect CSF and venous blood

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16
Q

two dense projections of inner dura layer:

A
  • Falx cerebri
  • Tentorium cerebelli
    and then continues as spinal dura
17
Q

which layer has vili/granulations that go through dura into venous sinuses to allow CSF flow into them?

A

arachnoid mater

18
Q

which layer is tightly fixed to the brain and SC surfaces?

19
Q

what is pia mater connected to?

A

arachnoid through arachnoid trabeculae (collagen fibers) to allow suspension of brain in CSF

20
Q

what secretes the most CSF?

A

Choroid plexuses

21
Q

formation of CSF includes:

A

a web of capillaries embedded in connective tissue and epithelial cells

22
Q

What is CSF and what is it composed of?

A

CSF is a protein rich substance.
Blood is filtered and transported through these layers to form CSF

23
Q

Color palate for CSF health

A

yellowish - infection
bright red - active hemorrhage
maroon red - venous blood

24
Q

What disorder is caused by quick accumulation of blood in a characteristic “lens” shaped accumulation?

A

Epidural Hematoma

25
What is epidural hematoma most likely caused by?
fracture of parietal or temporal bones leading to tearing of middle meningeal artery
26
Epidural hematoma is comprised of a period of ______, then quick ______.
lucidity; deterioration
27
Which disorder has a slow progressive deterioration (days to months) and most often due to venous bleed?
Subdural hematoma (not hemorrhage) - it is a lesser blood accumulation, common with older people when they fall. - different shape from epidural hematoma - bigger "C" on probably one side of the brain.
28
abnormal accumulation of CSF leading to increased pressure
Hydrocephalus
29
Symptoms of hydrocephalus in infants:
enlarged heads due to nonfused skull
30
Symptoms of hydrocephalus in children/adults:
excessive pressure especially of white matter due to fused skulls
31
Triad of hydrocephalus symptoms
1. worsening gait 2. incontinence 3. headache (HA) or cognitive deficits
32
What is normal pressure hydrocephalus (NPH)?
A type of communicating hydrocephalus where CSF builds up without a major increase in intracranial pressure.
33