Lecture 3 Flashcards
What are some skeletal tissues functions?
Support, protection, feeding, breathing, locomotion, mineral storage, endocrine (hormones), hematopoiesis (blood cells)
Skeletal tissue types
Cartilage, Bone, Bone Marrow
What are mature chondroblasts?
Chondrocytes
What do the mechanical properties of cartilage depend on?
all come down to the relative abundance of these components in the matrix (extracellular matrix)
True or false: cartilage is vascular
false: cartilage is avascular
How do gas & nutrients exchange from chondrocytes?
Diffusion
What is an osteoid
bone extracellular matrix
True or false: bone is vascular
true
What do osteoblasts produce
osteocytes
what do osteoclasts come from
fusion of macrophages
What do osteoclasts do?
secrete enzymes, eat away at extracellular matrix of the bone and take away
What is bone homeostasis regulated by?
osteocytes embedded in the matrix
What is the structural composition of bone dependent on?
bone homeostasis & resorption
How is dermal bone formed
Formed within the dermis through intramembranous ossification
What is dermal bone made of
calcium carbonate
What do crocodilians use osteoderms for?
to regulate blood pH and temperature
What intermembranous ossification
Bone forms on its own within a membrane (Membrane bone, Dermal bone)
What is endochondral ossification
a template made of cartilage is replaced by bone during development
Explain the steps of endochondral ossification
A template for the bone is made out of cartilage, Chondrocytes are now cut off from oxygen and nutrients so they start secreting help signals and the cartilage ECM begins to break down, Blood vessels are attracted to the chondrocyte’s help signals and infiltrate the center of the cartilage
Osteoblasts and osteoclasts hitch a ride on the blood vessels into the center of the cartilage template, Spongy (interior) and compact (exterior) bone replace the cartilage from the inside out.
This leaves a hollow center (medullary cavity) in the bone which is later filled with bone marrow and larger blood vessels
What is bone marrow
fatty (adipose) tissue which sometimes contains hematopoietic and osteogenic stem cells
Describe the skeletal tissue in agnathans
no bone, non-mineralized cartilage