Lecture 3 Flashcards

Gibbs free energy

1
Q

Energy is stored and captured into…

A

reduced bonds (C=O, C-C, C-H)

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2
Q

what can △G be calculated from?

A

Thermodynamic laws

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3
Q

The hydrolysis of ATP to ADP and inorganic phosphate releases

A

most of the △G in ATP

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4
Q

What is an anabolic process?

A

‘builds up’ organic molecules e.g. sugars, amino acids, etc.

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5
Q

What is a catabolic process?

A

Breaking down of molecules into CO2 and H20

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6
Q

Different food sources release different amounts of energy when…

A

combusted (burnt)

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7
Q

List these from the least to most amounts of energy released when combusted: protein, alcohol, carbohydrate, fat

A

Carbohydrate, protein, alcohol, fat

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8
Q

List these from the least to most amounts of energy released when metabolised: protein, alcohol, carbohydrate, fat

A

Alcohol, fat, protein, carbohydrate

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9
Q

Why is combustion different to metabolism? and then why use fat?

A

Enzymes work on CH and OH bonds. Molecules must be rearranged. Fat has slightly less energy per bond, but stores well, also fat can not be metabolised without O2.

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10
Q

What are the three stages of catabolism?

A
  1. hydrolysis of complex molecules to their building blocks (fats, proteins, polysaccharides)
  2. Conversion of these into Acetyl CoA
  3. Oxidation of acetyl CoA (oxidative phosphorylation produces ATP)
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11
Q

What are the three parts of ATP?

A

Adenine, ribose and triphosphate

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12
Q

Why does the third phosphate in ATP release the most energy when hydrolized?

A

Because the free electrons in the charged triphosphate are pushed towards the end due to the ribose and adenine group.

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13
Q

What is the first law of thermodynamics?

A

energy can not be created or destroyed, it changes form

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14
Q

What is the second law of thermodynamics?

A

The universe is becoming increasingly disordered.

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15
Q

What do the symbols stand for in this equation: △H - T△S = △G

A

change in enthalpy - Temp (change in entropy) = Change in gibs free energy

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16
Q

Does non-equilibrium mean the entropy will be lower or higher?

A

Lower

17
Q

What is ENTROPY a measure of?

A

A measure of disorder. e.g. 1 ATP to 2 ATP will be less ordered.

18
Q

Does equilibrium mean the entropy will be lower or higher?

A

Higher

19
Q

What is ENTHALPY a measure of?

A

Change in energy of reaction (work and heat)

20
Q

What does △G predict?

A

Whether a reaction occurs spontaneously. It predicts the max possible change in c between reactants and products, therefore showing how much you need for a reaction and how much it could make.

21
Q

The more negative △G is…

A

the more work can be done

22
Q

You need to keep the reactants as high as possible in order for a ____ reaction to occur

A

Exergonic (energy released)