Lecture 3 Flashcards
Gibbs free energy
Energy is stored and captured into…
reduced bonds (C=O, C-C, C-H)
what can △G be calculated from?
Thermodynamic laws
The hydrolysis of ATP to ADP and inorganic phosphate releases
most of the △G in ATP
What is an anabolic process?
‘builds up’ organic molecules e.g. sugars, amino acids, etc.
What is a catabolic process?
Breaking down of molecules into CO2 and H20
Different food sources release different amounts of energy when…
combusted (burnt)
List these from the least to most amounts of energy released when combusted: protein, alcohol, carbohydrate, fat
Carbohydrate, protein, alcohol, fat
List these from the least to most amounts of energy released when metabolised: protein, alcohol, carbohydrate, fat
Alcohol, fat, protein, carbohydrate
Why is combustion different to metabolism? and then why use fat?
Enzymes work on CH and OH bonds. Molecules must be rearranged. Fat has slightly less energy per bond, but stores well, also fat can not be metabolised without O2.
What are the three stages of catabolism?
- hydrolysis of complex molecules to their building blocks (fats, proteins, polysaccharides)
- Conversion of these into Acetyl CoA
- Oxidation of acetyl CoA (oxidative phosphorylation produces ATP)
What are the three parts of ATP?
Adenine, ribose and triphosphate
Why does the third phosphate in ATP release the most energy when hydrolized?
Because the free electrons in the charged triphosphate are pushed towards the end due to the ribose and adenine group.
What is the first law of thermodynamics?
energy can not be created or destroyed, it changes form
What is the second law of thermodynamics?
The universe is becoming increasingly disordered.
What do the symbols stand for in this equation: △H - T△S = △G
change in enthalpy - Temp (change in entropy) = Change in gibs free energy