lecture 3 Flashcards
what is a membrane
fluid and flexible barrier of phospholipids
not stabalized by covalent bond
how do membranes associate?
hydrophobic interactions
what kind of barrier do membranes have?
semipermeable
what are membranes permeable too?
O2, H2O, CO2, small non-polar molecules (cholesterol, glycerol)
what are membranes impermeable too?
large molecules, ions, charged molecules (polar)
how do permeable molecules move?
passive diffusion
how do impermeable molecules
can move via. facillitated diffusion or active transport
how does passive transport work?
permeable substances move down the gradient and across the barrier
what is hypotonic (passive transport)?
explode
water rushes into the cell
high solute inside, low solute outside
what is hypertonic (passive transport)?
shrink
water rushes out
low solute inside, high outside
what is facilitated diffusion?
transport down a concentration gradient that uses protien transmitter
what is active transport?
transport of molecules up the concentration gradient using energy
active transport 1° example?
sodium potassium pump
how does sodium potassium pump work?
first site, 3 Na+ out for every 2 K+ in
powered by atp, attaches phosphate on causing change in shape
second site, Na+ and glucose brought in
what are the two sections of 2° active transport?
cotransport - transport of 2 molecules/protiens
coupled transport - one gradient is used as an energy source to power another
what are the two types of cotransport
symport: 2 molecules same direction
anytiport: 2 molecules opposite direction
bulk transport
molecule must enter/exit but is too large
bulk transport example
cargo moves through golgi via cisternal maturation
vesicle recyling to keep cisternae unique, move in anterograde fashion
vesicle moves along tubules using kinesin
hormones and secreted in plasma membrane
phagocytosis
cell eating of a specific ligin
phagocytosis steps
ligin is brought in
receptor mediated endocytosis attaches to plasma membrane
clarithin brings receptors together
ligin moves to vesicle
ligin moves to lysosome