Lecture 3 Flashcards
Hydrophilic
High affinity for water and is soluble
Hydrophobic
Low affinity for water and is non-soluble
Macromolecules
Large molecules generated by the polymerization of small organic molecules
Monomers
The repeating units which make up polymers
Cellular Hierarchy
Biological molecules and structures are organized into a series of levels, each building on the preceding one
Supramolecular Structures
Components of organelles and other subcellular structures that make up the cell
Principle of Self-assembly
The information needed to specify the folding of macromolecules and their interactions to form complex structures is inherent in the polymers themselves
Chemical Simplicity
Relatively few subunits are used for a wide variety of structures
Efficiency of Assembly
A small number of kinds of condensation reactions are needed (enzymes)
Quality Control
Defective components can be discarded prior to incorporation into higher-level structure, reducing the waste of energy and materials
Enzymes
Function as catalysts, increasing the rate of chemical reactions
Structural Proteins
Physical support and shape
Motility Proteins
Contraction and movement
Regulatory Proteins
Control and coordinate cell function
Transport Proteins
Move substances in and out of cells
Hormonal Proteins
Communication between cells
Receptor Proteins
Enable cells to respond to stimuli from the environment
Defensive Proteins
Protect against cell damage and pathogens
Storage proteins
Reservoirs of amino acids
SH2 Domain
Structural module that binds tyrP
Activities
Any abilities that a protein has can be referred to as an activity
Polypeptide
The immediate product of amino acid polymerization
Protein
A polypeptide that has been folded into a functional three-dimensional structure
Multiprotein Complexes
Assembled complexes made of more than one macromolecule
Electrophoresis
Using an electric field to separate charged molecules
Plasmids
Small, circular DNA molecules that can autonomously replicate in bacteria
Polysaccharides
Long chain polymers of sugars and sugar derivatives that are not informational molecules
Microvilli
Fingerlike projections that increase the surface area
Cytoplasmic Streaming
Propellers are used to move cytoplasmic contents and aid in diffusing nutrients