Lecture 27: Steroid Hormones Flashcards
1
Q
Steroid hormone classes
A
Corticosteroids (adrenal cortex)
1. Glucocorticoids
2. Mineralocorticoids
Sex steroids (testes/ovaries)
3. Androgens
4. Estrogens
5. Progesterone
2
Q
Addison’s disease
A
Chronic adrenal insufficiency
Pituitary disease with failure to make cortisol/aldosterone
3
Q
Cushing Syndrome
A
Sustained hypersecretion of glucocorticoids; can be caused by extended high dose corticosteroid meds
4
Q
Genetic sex determination and development
A
Y chromosome has active SRY gene, which initiates testes development thru testosterone production
5
Q
Active form of testosterone
A
Testosterone is often converted to active form DHT in target tissues by 5 alpha hydroxylase
