Lecture 24 Flashcards
1
Q
What are mutations
A
permanent changes to DNA sequence
2
Q
What are germline mutations
A
inherited - passed through gametes
3
Q
What are somatic mutations
A
not passed on - changes to DNA
4
Q
What is a dominant mutation
A
causes phenotype when heterozygous
5
Q
What is a recessive mutation
A
only causes phenotype when homozygous
6
Q
What is a loss of function mutation
A
breaks gene or causes it to not work as well as normal
can often recessive - normal copy replaces function
7
Q
What is a gain of function mutation
A
causes a gene to work too well or do something unexpected
often dominant
8
Q
What are polygenic disorders
A
involve several genes acting together or evniromental factors interacting with genes
e.g obesity
