Lecture 2 - The structure of the Atom Flashcards
what are protons and neutrons called?
nucleons
what are isotopes?
atoms with the same atomic number and different mass number, they have the same chemical properties
what is the kinetic isotope effect?
heavier isotopes react slightly slower
what is the H3 isotope mainly used for?
it’s radioactive and used in labelling experiments
Describe unstable isotopes (radioactive isotopes)
they undergo spontaneous disintegration in order to become a stable nucleus, this results in emission of small particles and radiation
How are isotopes detected?
during mass spectrometry, it measures the molecular weight of atoms by observing the mass to charge ratio of ions
what are some applications of mass spectrometry?
determining isotopic abundance, identification of small molecules and proteins
what can calcium isotopes be used for?
osteoporosis research
what can carbon-13 isotopes be used for?
looking at molecular structure and chemical research
what can copper isotopes be used for?
noninvasive studies of copper metabolism
what can helium isotopes be used for?
in vivo magnetic resonance studies
what can hydrogen isotopes be used for?
vitamin research
what can iron isotopes be used for?
metabolic tracer studies to identify genetic iron control mechanisms
what can krypton isotopes be used for?
diagnosis of pulmonary disease
what can nitrogen isotopes be used for?
whole body protein turnover, synthesis and catabolism
what can oxygen isotopes be used for?
lean body mass measurements and obesity research
what particles/radiation could be emitted during radioactive decay?
alpha, beta and gamma
what is half life?
time taken for the activity of a given amount of a radioactive substance to decay to half its initial value
Describe alpha decay
emission of an alpha particle, which is a helium nuclei, positively charged
Describe gamma radiation
- emission of a gamma photon -High frequency electromagnetic radiation
- neutral charge
- no effect on atomic or mass number
- often produced along with alpha or beta
Describe beta minus decay
emission of an electron
Describe beta plus decay
emission of a positron (an anti electron) atomic number decreases
what is the capture process?
where a small particle is collides with he nucleus and is added to it
what is an industrial application of unstable isotopes?
- energy generation
- sterilisation of food and medical supplies
what is a domestic application of unstable isotopes?
smoke detectors using Am241
what is a medical application of unstable isotopes?
- diagnostic uses
- therapeutic -weakening or destroying particular targeted cells
Describe medical imaging used with unstable isotopes
a radioisotope used for diagnosis must emit gamma rays of sufficient energy to escape from the body and it must have a half-life short enough for it to decay away soon after imaging is completed
Describe therapy using unstable isotopes
selective damage to unhealthy tissue, a radioisotope used for therapy should be a strong beta emitter to damage cells in small areas