Lecture 2: Stem cell technology & society

Question 1

mammalian life cycles can be thought of as

Answer 1

a germ cell cycle. + can be manipulated at different points

Question 2

Technologies affecting stem cells. 2 broad categories

Answer 2

-Genetic technologies
-Reproductive technologies
TOGETHER these technologies are potentially a powerful way to potentially MANIPULATE humans

Question 3

Examples of genetic technologies

Answer 3

• sequencing
• Genetic manipulation (CRISPR etc)
• Artificial chromosomes

Question 4

examples of Reproductive technologies

Answer 4

• IVF
• ES cells
• iPS cells
• in Vitro gametogenesis
• Cloning

Question 5

HAC (human artificial chromosome) consists of

Answer 5

1) “replication origin” necessary for DNA duplication
2) “centromere” enable, proper chromosome
3) “telomere” protects the ends of linear chromosomes

Question 6

Generating transgeincs

Answer 6

• can inject DNA into the embryo
• e of the mice produced have germ cells
• breed and check offspring for gremlin mutations