Lecture 2 Sexual Production: What Is It and Why? Flashcards

1
Q

What is sexual reproduction?

A

Perpetuation of the species

Requires male and female gametes (halving of chromosomes) then subsequent fertilisation

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2
Q

What are the advantages of sexual reproduction?

A

Hybrid vigour
Genetic variation and evolutionary flexibility
Maximise individual and species survival
Ability to respond rapidly to changes

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3
Q

What are the disadvantages of sexual reproduction?

A

Requires both male and female (sometimes not both available in the population)

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4
Q

What are some possible solutions if both sexes are not present in the population?

A

Parthenogenesis, gynogenesis, hybridogenesis

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5
Q

What is parthenogenesis?

A

Within the female, cells duplicate without to make a replicate of itself with no male genetic material. Either by moving from female egg cell (2n) to diploid egg (2n) without division so diploid thus no need for fertilisation. Or normal oocyte (n) is fertilised with another oocyte (n) to form diploid zygote

/main solution we learn about, only female!

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6
Q

What is gynogenesis?

A

Female produces eggs with the full complement of chromosomes (2n) but relied sperm from any other species to activate zone pellucida causing growth of ovum but only retains genetic material of ovum

/’gyno-‘ means women, so out of gynogenesis and hybridogenesis, gynogenesis is more reliant of women

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7
Q

What is hybridogenesis?

A

Female produces haploid eggs which are fertilised by a male that must be from a closely related species causing development. So the hybrid organism will have genetic material from both male and female species. However during gametogenesis, the hybrid eliminates genetic material from male and only retains the original female to form ovum.

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8
Q

Which animals are amniotes?

A

Mammals, reptiles, birds

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9
Q

Which animals are anamniotes?

A

Amphibians, fish

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10
Q

What are amniotes?

A

Developing embryos have an amniotic membrane, a specialised formation of extra embryonic membrane which surrounds the developing embryo and fills with cushioning amniotic fluid. Internal fertilisation. Amniotes bypass the aquatic larval stage due to fluid around amnion providing nutrition. Reptiles and birds lay cleidoic eggs on land, the egg contains all the food the embryo needs to develop into a hatchling. Mammals have evolved to live birth.

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11
Q

What are anamniotes?

A

Developing embryos do not have amniotic membrane. Secondary egg cells are laid into water, where fertilisation takes place externally

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12
Q

How are vertebrates categorised into modes of sexual reproduction?

A
Vertebrate group (taxa): mammals, reptiles, birds are amniotes. Amphibians, fish are anamniotes
Environmental conditions
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13
Q

What is oviparity?

A

Oviparous animals lay eggs only

All birds, most fishes, amphibians and reptiles

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14
Q

What is viviparity?

A

Viviparous animals give birth to live young.
There is a continuum of minimal to invasive embryo dependence on the mother
Ovoviviparity: embryo develops inside mother but does not rely on her for nourishment
Viviparity: embryo develops inside mother and dependent on her for nourishment.

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15
Q

What is genotypic sex determination?

A

Determined at fertilisation because male and females have different chromosomal karyotypes. Leads to formation of separate sex-specific reproductive tracts.

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16
Q

Outline mammalian genotypic sex determination

A

Male: heterogametic X and Y sex chromosomes + 22 autosomal pairs
Female: homogametic 2 X sex chromosomes + 22 autosomal pairs

17
Q

Outline bird genotypic sex determination

A

Male: homogametic 2 Z sex chromosomes + 22 autosomal pairs
Female: heterogametic W and Z sex chromosomes + 22 autosomal pairs
Same with snakes

18
Q

What is dosage compensation?

A

In female mammals there are 2 X chromosomes which is more than required so 1 X chromosome is switched off in blastocyst stage. However in male birds require both Z chromosome to be male, no dosage compensation

19
Q

Name the key molecules in Sertoli cell/testis development and their functions.

A

Sex-determining region Y (SRY) in mammals: promotes downstream hormonal control of developing reproductive tract
DMRT1 in birds: controls genotypic sex in each cell (cell autonomous)
SRY-box genes (Sox9) in all vertebrates: signals for AMH
Anti-Mullerian hormone (AMH) in all vertebrates: suppress female reproductive tract development

20
Q

Name the key molecules in ovarian development and their functions.

A

Ovarian aromatase: converts androgens to oestrogens

Forkhead box genes (FOXL2): promote ovarian development

21
Q

Has there been reduction in Y chromosome genetic material, why or why not?

A

Have lost most of the genetic material because only SRY is required for male determination

22
Q

Is there high or low prevalence of polymorphisms in the Y chromosome, why?

A

Accumulation of single nucleotide polymorphisms more than other chromosomes because only part of chromosome used for maleness, lots of freedom for polymorphisms without affecting maleness or population

23
Q

What is sequential hermaphroditism?

A

First female then male or first male then female. Due to the sequential expression of genes regulating gonadal aromatase (CYP19a1a) thus affecting oestrogen production and ovarian development

24
Q

What is protogynous fish?

A

First female (gyn-) then male

25
Q

What is protandrous fish?

A

First male (andr-) then female

26
Q

What is the mechanism for temperature-dependent sex determination?

A

Not full elucidated but postulate that:
Female-specific temperatures will induce expression of aromatase CYP19a1a causing androgens to oestrogens within the developing gonads.