Lecture 2 - Receptors Flashcards
Free Nerve endings
Mostly unmyelinated have small sensory terminals that act as cation channels that respond to temperature, pain, movement, pressure.
Some wrap-around hair follicles and act as light touch receptors
Tactile discs
Free nerve endings which are located in the deepest layer of the epidermis. They are abundant in the fingertips and have large disc-shaped epidermal (Merkel) cells. Sensitive to texture, shapes and edges.
Tactile corpuscles
Located in the papillary layer of the dermis. They are unmyelinated sensory terminals surrounded by modified schwann cells and a thin oval of fibrous connective tissue. They detect fine touch, deep pressure and low frequency
What does deformation of the capsule in tactile corpuscles trigger?
The entry of Na+ ions into the nerve terminal
Lamellar corpuscles
Scattered deep in the dermis and hypodermis. Dendrite lying in layers of collagen and fibroblasts. Deformation of the capsule opens pressure sensitive Na+ channels in sensory axon.
Bulbous corpuscles
Located in the dermis and subcutaneous tissue. Also found in joint capsules. Network of free nerve endings twisted with a core of collagen fibres. Capsule surrounds the entire structure