Lecture 2: Population-level study design Flashcards
What is Humourism?
Ill health caused by imbalances in four fundamental characteristics
Humorism was based on the idea that four essential fluids (blood, yellow bile, black bile, and phlegm) in the body controlled a person’s health and personality
What are the 4 characteristics of Humourism?
- Incorporated roles of temperament.
- Seasons
3.Climate - Alchemic elements
What treatments were used during Humourism?
Blood letting
Laxatives
Emetics
What did Vrchov introduced to western medicine?
Cellular Pathology
(1840s)
What did Snow introduce to western medicine?
Epidemiology
(1850s)
What did Pasteur introduce to western medicine?
Microbiology
(1860s)
What does the practice of Evidence based medicine intergrate?
1) individual clinical expertise
2) the best available external clinical evidence
3) Patient values & expectations
How do you formulate an Evidenced based Medicine research Questions?
(5 As cycle)
- Ask: Formulate a research question
- Access: Find and retrieve the ‘best evidence’
- Appraise: Consider the evidence for its validity & relevance
- Apply: Integrate the of results into clinical practice
- Assess: Evaluate the effectiveness
Which type of studies contains filtered infromation?
Critically-Appraised Individual articles
Critically Appraised Topics (Evidence Syntheses)
Systematic Review
Which type of studies contains filtered information?
Critically-Appraised Individual articles
Critically Appraised Topics (Evidence Syntheses)
Systematic Review
Which type of studies contains unfiltered information?
Randomised Controlled Trials
Case-Controlled Studies
Cohort Studies
What type of studies does the TRIP data base Seach for simultaneously?
Background Information/Expert Opinion
What are the 4 types of evidence?
- Description
- Prediction
- Casual Inference
- Qualitative
What is description evidence?
What happened?
Who was affected?
People with X had Y
What is Prediction evidence?
What will happen?
Who will be affected?
People with X are more likely to have Y?
What is Casual Inference evidence?
What will happen if…?
Why were they affected?
If we changed X, how would it change Y?
What is Qualitative evidence?
What matters…?
Why does it matter?
How can we effectively change X…?
Should we change X?