Lecture 2 Membrane Transport

Question 1

What forces drive solutes from one side of the membrane to the other?

Answer 1

Concentration Gradient and electrochemical gradient

Question 2

What solute properties dictate its permeability?
Why can some solutes passively diffuse through the plasma membrane, and some cannot?

Answer 2

Hydrophobic and gasses
Small uncharged polar molecules
large uncharged polar molecules
Ions

Question 3

Compare and contrast
– passive diffusion vs. passive carrier-mediated transport

Answer 3

Passive diffusion do not need something to help move it across membrane
passive carrier mediated is when it needs help from another molecule

Secondary Active transport used energy of an Ion’s E- Chem Gradient

Question 4

Compare/contrast
– passive carrier-mediated transport vs. active carrier-mediated transport

Answer 4

Passive Carrier mediated transporter uses a TRANSPORTER(carrier protein) to be able to go through the membrane

Passive goes w/ its concentration of the carrier
Active goes against the concentration and needs ATP to help mediate needs a confirmation change to help.

Question 5

Types of primary Active transporters
(USE ATP)

Answer 5

P-Class: ATPASE(NA/K and CA)

ABC Family: Flipase/Flopase

Question 6

Explain Secondary Active Transport Via GLUT

Answer 6

Glucose used NA+ conc gradient(High to Low) to power glucose uptake from low to high conc.

Question 7

Differentiate the different types of
– Channel gating

3 types

Answer 7

Channel Gated usually passive because responds to a signal from the cell

Voltage:

Ligand:

Mechanical

Question 8

– Carrier-mediated transport (uniport, symport, antiport)

Answer 8

Uniport: Transmembrane of a single molecule
Symport: Simultaneous movement of two molecules
Antiport: simultaneous movement of two molecules in opposite direction.

For Symport and Antiport they use one fo the conc gradients to harness energy to move