lecture 2: classification of viruses

Question 1

where do viruses get their names?

Answer 1

anatomical sites, disease association, person who discovered virus, biochem attributes, infected cell attributes, symptoms of disease

Question 2

virus classification: family

Answer 2

viridae, all different virus in the group, closely related

Question 3

virus classification: genus

Answer 3

virus, grouping of virus, beta, alpha, etc.

Question 4

virus class: species

Answer 4

individual virus

Question 5

what is a strain?

Answer 5

virus with slightly different genomic sequence

Question 6

what is a serotype?

Answer 6

virus with different antibiotic response

Question 7

what is a quasi species?

Answer 7

when many minor mutations accumulate in a person

Question 8

what are the components of a virus

Answer 8

nucleic acid genome (RNA or DNA)
capsid called a nucleocapsid

Question 9

What are the components of a capsid

Answer 9

protomers that make up the capsomers, capsomers that make up the capsid

Question 10

What is the advantage of an enveloped cell?

Answer 10

Host cannot distinguish as foreign

Question 11

What is an enveloped cell?

Answer 11

Have membrane/bilayer that is picked up when budded out

Question 12

What are the components of an enveloped cell?

Answer 12

envelope, nucleocapsid, matrix proteins that anchor the envelope to the capsid, glycoproteins that are receptors for viral particles

Question 13

how is a viral genome organized?

Answer 13

can be ran or dna, single Orr double strand, circular or linear, single unit or segmented, usually one copy of genome

Question 14

How man y genome copies are in a retro virus?

Answer 14

3

Question 15

What are the pros and cons of DNA virus?

Answer 15

pro: can use cell machinery
con: must cross nuclear membrane

Question 16

What are the pros and cons of (+) RNA virus?

Answer 16

pro: don’t cross nuclear membrane->can be translated immediately without proteins
con: must make protease to overcome one gene= one protein