Lecture 2: Cell Membrane And Membrane Transport Flashcards

1
Q

2 properties of particles that influence their permeability

A

-solubility of particle in lipid (charge)
-size of particle

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2
Q

4 types of passive transport

A

-diffusion
-osmosis
-channel mediated
-facilitated diffusion

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3
Q

diffusion aka

A

simple diffusion

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4
Q

simple diffusion

A

movement of solutes across lipid bilayer from high to low concentration

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5
Q

osmosis

A

diffusion of water across membrane

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6
Q

channel mediated transport

A

diffusion through a protein channel (ion channel)

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7
Q

facilitated diffusion

A

carrier mediated diffusion

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8
Q

2 types of active transport

A

-primary
-secondary

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9
Q

both types of active transport involve

A

moving solutes against concentration gradient, requiring energy

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10
Q

diffusion depends on what

A

brownian motion - random thermal motion of molecules

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11
Q

what is fick’s law of diffusion: general

A

-various factors affect diffusion rate
-net rate of diffusion is proportional to concentration gradient

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12
Q

what are the factors that affect diffusion rate (5)

A

-concentration gradient
-surface area of membrane
-lipid solubility
-molecular weight of substance
-distance (thickness) of membrane

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13
Q

which factors increase net diffusion rate (3)

A

-concentration gradient
-surface area of membrane
-lipid solubility

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14
Q

which factors decrease net diffusion rate

A

-molecular weight of substance
-distance/thickness

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15
Q

channel mediated transport: gated ion channel

A

-open in response to stimulus
-allow many ions in at once
-specific to ion

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16
Q

the sodium potassium pump is an example of what kind of transport

A

primary active transport

17
Q

primary vs secondary active transport

A

-primary: ATP binds to the transporter
-secondary: ATP not directly used

18
Q

what kind of transport is glucose transport

A

secondary

19
Q

difference between carrier mediated transport and simple diffusion: transport rate v concentration

A

-transport maximum exists for carrier mediated transport as carriers will become occupied
-simple diffusion is linear, no limit

20
Q

how does water move during osmosis

A

to area of higher solute concentration

21
Q

higher solute concentration = _________ concentration of water

A

lower

22
Q

what kind of transport protein is used in the movement of water

A

aquaporins

23
Q

semi permeable membrane

A

-membrane is permeable to water but impermeable to solute
-only water moves
-causes increase in volume
-hydrostatic pressure and osmotic pressure are in equilibrium

24
Q

osmolarity/osmolality definition

A

total concentration of particles per amount of solution

25
Q

is osmolarity of intracellular and extracellular fluids the same or different

A

same

26
Q

what happens if there is a higher concentration of an impermeable substance inside the cell

A

water is forced to move and cell volume and shape change

27
Q

tonicity

A

ultimate effect a solution has on cell volume which determines whether cell size remains the same, swells or shrinks when a solution surrounds the cell

28
Q

effective osmolarity

A

-osmolarity of non permeable particles in solution
-control actual movement of water

29
Q

Osmolarity vs osmolality

A

-osmolarity is a volume measure
-osmolality is a mass measure