Lecture 2 Cell Membrane Flashcards
Roles of cell membrane
- Selective barrier
- Transport
- Communication & cell signalling
- Cell adhesion
Composition of cell membrane
• Lipids 40%
• proteins 50%
• Glucids 10%
Lipids
Phospholipids
- The barrier function of the cell membrane.
- The fluid and dynamic character of the cell membrane necessary for carrying out various cellular activities
Lipids
Cholesterol
stability, rigidity
Lipids
Glycolipids
Rare, external layer
Proteins
Intrinsic
Covalent bonds with lipids in the bilayer
Proteins
Extrinsic
Ionic bonds with lipids or integral proteins
Proteins
Outside the cell =
Ectoproteins
Proteins
Inside the cell =
Endoproteins
TRANSPORT OF IONS AND SMALL MOLECULES
- Diffusion
• simple diffusion
• Facilitated Diffusion - Active transport
• Direct active transport
• indirect active transport
TRANSPORT OF MACROMOLECULES AND PARTICLES
Exocytosis = the process by which the macromolecules synthesized in the cell are packed into vesicles, transporters and eliminated into the extracellular environment.
Constitutive exocytosis
- the continuous elimination into the extracellular environment
Regulated exocytosis
- in specialized cells that temporarily store synthesized proteins in secretory vesicles and remove them into the extracellular environment only after a specific stimulus