Lecture 2 - Cancer And Exercise Flashcards
Side effects/Adverse events of Cancer and it’s Treatment.
Increased:
-fatigue, depression, anxiety, weight gain, risk of other cancers, CVD, diabetes and osteoporosis risk, functional decline
Decreased:
-physical activity, QOL.
Benefits of increasing PA:
Decreases side effects/adverse events of diagnosis, surgery and treatment:
- Decreased fatigue, depression and anxiety, CVD , diabetes, and osteoporosis risk, risk of recurrence, risk of new cancers, all cause mortality risk.
- Increased: QOL, weight loss and weight maintenance, overall survival, cancer specific survival.
Why recommend exercise to cancer patients and survivors?
Many cancer patients and survivors have lifestyles that could contribute to a recurrence an/or poor QOL
Exercise and prostate cancer survival: Statistics
Men with > 3 hrs per week of vigorous activity had a 49% lower risk of all-cause mortality.
61% lower risk of PCa death.
Benefits for symptoms and toxicities:
Aerobic exercise= reduced nausea & body fat.
Decreased = fatigue,
Increased = muscle function, physical performance, aerobic exercise, QOL, body comp.
General increases=
- muscle and bone tissue mass
- cardiorespiratory fitness
- max walk distance
- immune system capacity
- physical functional ability
- flexibility
- muscle strength
- QOL
- haemoglobin
General Decreases=
- Nausea
- body fat
- fatigue
- symptom experience
- duration of hospitalisation
- anaerobic energy reliance
- heart rate
- resting systolic BP
- insulin and IGF1
- Estrogen in women
- psychological and emotional stress
- depression and anxiety
Benefits of exercise before cancer treatment:
Exercise intervention pre-treatment:
- high completion rates and adherence
- improves muscle strength, cardiorespiratory fitness, motivation.
Benefits of Exercise During cancer treatment:
Reduced :
- incidence and severity of fatigue
- incidence and severity of depression
- incidence of lymphoedema
- incidence and severity of anxiety
- incidence and severity of sleep disorders
Improved positive mood
Increases physical reserve capacity
Benefits of Exercise Following cancer treatment:
Improved functional capacity
Reduced incidence & severity of comorbid conditions
Improved overall QOL
Improved survival
Generic exercise prescription:
Mode- Aerobic= 150min p/w moderate intensity [RPE 5-6 out of 10]
120 min p/w vigorous intensity [RPE 7-8 out of 10]
- Resistance = 6-10 exercises, 6-12RM, 2-3x p/w, 3-4 sets per exercise.
ACSM Roundtable on Exercise guidelines for Cancer Survivors:
Exercise is safe during and after cancer treatments
Results in improvements in physical functioning, QOL, and cancer-related fatigue in several cancer survivor groups
Cancer survivors to follow PA Guidelines, with specific exercise programming adaptations based on disease and treatment-related adverse effects
Advice to “avoid inactivity” even during difficult treatments
Overall objectives of exercise prescription:
- regain and improve functioning, aerobic capacity, strength, flexibility
- improve body image and QOL
- improve body composition
- potentially reduce or delay reoccurrence
- reduce and prevent long-term and late side effects of treatment
- improve capacity to withstand future treatments
Principles of Exercise Testing and Prescription:
Each parameter measured must be relevant to the improvement of cancer survivor’s outcomes
All procedures valid and reliable
Protocols consistent and rigidly controlled
Patient’s rights protected
Testing repeated at regular intervals
All results reviewed and discussed with patient
Report provided to referring doctor
Tests inform the exercise prescription
When do you need a Medical clearance:
If patient is over 35yrs of age
Has any primary risk factors for cardiovascular diseases such as: family history of heart attack or stroke, high BP, high cholesterol, existing cardiovascular disease
Overweight
-need to consult doctor before starting an exercise program