Lecture 2 - Antepartum Family & Fetal Development Flashcards
What is supine hypotension?
When a pregnant patient lies supine and the weight of their abdomen compresses their vena cava and aorta - causes pre/syncope and hypoTN.
Intervention: Position pt on side until S/S subside and vitals stabilize.
What are the three stages of uterine development?
Menstruation (day 1) - shed on lining
What are the three stages of intrauterine development?
- Ovum/Pre-embryonic (Conception-Day 14)
- Embryo (Day 15-8 weeks)
- Fetus (9+ weeks)
What are the three primary germ layers? When are they differentiated?
Differentiated during 3rd week following conception
Ectoderm, Mesoderm, Endoderm
What is ectoderm?
Upper layer of embryonic disk
–> epidermis, NS, skin, nails, hair
What is mesoderm?
The middle layer of embryonic disk
–> Bones & teeth, muscles, circulatory systems
What is endoderm?
Lower layer of embryonic disk
–> digestive system, lungs, liver, glands
What is chorion?
The outermost fetal membrane - covers the fetal side of the placenta. Contains major umbilical blood vessels that reach over surface of the placenta.
What are the two layers of embryonic membranes?
Chorion - outermost
Amnion - innermost
What membrane holds amniotic fluid?
The amnion - innermost membrane
How much amniotic fluid is prevent at term?
700-1000 mL
What are the purposes of amniotic fluid?
–> Maintaining body temperature
–> Barrier from infection
–> Cushion to protect fetus and umbilical cord
–> Enhancing fetal lung development by filling lungs and expanding alveoli
–> Encourages symmetrical growth
What is oligohydramnios? What is it associated with?
Having less than 300mL of amniotic fluid
–> Associated with fetal renal abnormities
What is polyhydramnios? What is it associated with and what complications can it cause?
More than 2L of fluid
–> Associated with GI and other malformations
–> Risk of pre-term labour, subinvolution (PP hemorrhage), risk of cord prolapse and issues with engagement.
What is a yolk sac? What is its purpose? When does it disappear?
Aids in transferring maternal nutrients and oxygen which have diffused through the chorion to the embryo.
–> Completely separated from the embryo by week 5-6
What are chorionic villi?
Villi that branch from the chorion and burrow into the uterine lining - areas of gas and nutrient exchange.
Maternal blood is present in subvillous space.
When does the umbilical cord develop? How many blood vessels does it have?
Develops from the connective stalk by end of 5th week.
–> 2 arteries, 1 vein.
How long is the umbilical cord?
Ave 55 cm at term
What is Wharton’s jelly?
A mucoid connective tissue that prevents compression of blood vessels in the umbilical cord.
What is a Nuchal cord?
When the umbilical cord is wrapped around the fetal neck.
–> Document how many times it is wrapped
cont page 199 for cotyledons
What are the primary components of preconception care?
- Health promotion
- Risk factor assessment
- Interventions
What is a definition of infertility?
Those below the age of 35 who have been trying to conceive for a year.
When is the first week of a pregnancy?
First day of last menstrual period
Egg matures in ovaries from day 1-14, ovulation occurs on day 14
When is the fertile window?
Days 11-14 of menstrual cycle
What is lanugo?
Fine hair. Falls off round the 35 week mark
–> More common in pre-term babies.
What is the age of viability?
The age at which a baby has a reasonably good chance of surviving outside the uterus
–> 22-25 weeks at present with NICU support.
What is a zygote?
First 2 weeks of pregnancy
–> From fertilization to implantation.
What is gestational vs postconception age?
Gestational Age
–> Based on first day of last period
Postconception Age
–> Begins two weeks after last period - used when speaking about fetal development
Why is the 4-5 week mark of embryonic so significant?
Formation of most vital organs, hematopoiesis.
What is quickening?
When childbearing person begins to feel fetal movement
–> 18 weeks for first pregnancy, 16 weeks in following pregnancies.
When does sex differentiation occur in fetal development?
possible by week 12.
Teratogens have the largest impact on fetal development in the first ____ weeks.
12
When is the placenta complete?
It is structurally complete at 12 weeks and continues to widen until 20 weeks. Then continues thickening.
What hormones are released by the placenta?
HGH, progesterone, estrogen, HPL (chorionic somatomammotropin)
What is the source and effects of HCG?
slide 23
progestrone
slide 23
estrogen
23
HPL
23
What are normal findings for the umbilical cord?
–> Vessels, length, location on placenta
AVA, 55cm, located centrally on placenta.
What are the three shunts seen in fetal circulation?
Ductus arteriosus
–> Between pulmonary arteries and
slide 26/7
Oxygenated blood from the placenta enters fetal body through umbilical vein. It is then shunted where by what structure?
Majority is shunted via ductus venosus into inferior vena cava, bypassing liver.
Enters R-atrium
right atrium
slide 27
right ventricle part two
27
What causes the foramen ovale to close into the fossa ovalis after birth?
Changes in pressure
–> Lower in RA and higher in LA following birth
What causes the ductus arteriosus to become a ligament following birth?
increase in oxygen levels
What causes the ductus venosus to change into a ligament following birth?
Closes with clamping of cord and d/t BV constriction caused by cold air and changes in oxygen.
What are dizygotic twins? How do they share….
Fraternal
–> Each with their own chorion, amnion, and placenta.