Lecture 2 Flashcards
Whats epithelial tissue?
Tissue composed of layers of closely spaced cells that cover organ surfaces, form glands and serve for protection, secretion and absorption.
Whats connective tissue?
Tissue with more matrix than cell volume, often specialised to support bind together and protect organs
What’s nervous tissue?
Tissue containing excited cells for rapid transmission of coded information to other cells
Whats muscular tissue?
Tissue composed of elongated, excitable cells specialised for contraction
Whats Osteology?
The study of bone
What tissue does the skeletal system consist of?
Bone - osseous tissue has a matrix that is hardened by calcium phosphate and other minerals
Cartilage - forerunner of most bone; covers bones at joint surfaces
Ligament - holds different bones together at joints
What is the function of the skeleton? 6
Support
Protection
Movement
Electrolyte balance -stores calcium and phosphate ions and releases them into fluid according to physiological needs
Acid-base balance - buffers the blood against excessive pH needs by absorbing and releasing alkaline salts.
Blood formation - red bone marrow is a major producer of blood cells.
What are the types of bones?
- long bones
- short bones
- flat bones
- irregular bones
What are the features of long bones? 5 marks
- Hard shell of compact bone
- medullary/ marrow cavity
Bone marrow in centre
Spongy bone at ends - diaphysis - shaft, provides leverage
- epiphysis - large surface area for articulation
- Epiphyseal line - region of bone growth
Features of flat bones 3m
- Diploe serves to absorb impact and prevents fractures of inner compact bone
- periosteum on both sides
- endosteum lining the diploe
What are the types of bone cells and what are there uses? 8
Osteoprogenitor cells- precursor to osteoblasts, growth factors.
Osteoblasts- build bone, non mitotic, synthesise organic bone matrix, increase response to mechanical stress
Osteocytes - branches communicate and sense mechanical stress.
Osteoclasts- reabsorb bone .
Whats bone matrix made of? 6
It’s made if 1/3 organic and 2/3 inorganic substance
Organic:
- collagen
- proteins
Gives it flexibility
Inorganic
- 85% hydroxyapatite (crystallised calcium phosphate) , 10% calcium carbonate
- allows load bearing without deformation
- laid down when solubility product is exceeded
What is calcium in the body responsible for? 5
- neuron communication
- muscle contraction
- blood clotting
- cell signalling
- co-factor of enzymes
What happens when there’s low blood calcium?
- Excessive excitability of the nervous system, muscle spasms, tremors, tenany
What happens when there’s high blood calcium?
-depression of the nervous system, muscle weakness, emotional disturbance, sluggish reflexes and cardiac arrest.