Lecture 2 (8/29) Flashcards
Provides an ideal environment for bacterial colonization:
root canal system
Why is the RC system an ideal environment for bacterial colonization?
- warm
- moist
- nutritious (has lots of substrate)
Describe the climate of the RC system:
variable but largely anaerobic climate
What allows the RC system to be largely protected from the host defenses?
due to lack of circulation in a diseased pulp
What does the lack of circulation in a diseased pulp allow for?
The area to be protected from the host defenses
Because the root canal system of a diseased pulp does not have circulation allowing it to evade host defenses, it is considered a:
privileged sanctuary
The basic science most closely associated with the practice of endodontics:
microbiology
By using a special “anaerobic glove box: technique, ____ were successfully cultured from the canal system
anaerobic bacteria
Sundqvist proved that many of the pathological bacteria found in the root canal system are:
black pigmented anaerobic gram negative rods
The black pigmented anaerobic gram negative rods found in the RC system: (6)
- porphyromonas
- prevotella nigrescens
- peptostreptococcus
- fusobacterium
- eubacterium
- actinomyces
Black pigmented anaerobic rods found in the RC system release:
Lipopolysaccharides (LPS), also known as endotoxins: fever, collagenolysis, osteolysis
The LPS (also known as endotoxins) released by the black pigmented anaerobic rods can cause:
- fever
- collagenolysis
- osteolysis
The root canal walls/spaces are conductive for the formation of:
biofilm
A complex, colonized community of bacteria:
biofilm
In an infection, ____ is adhered to the root canal walls
biofilm
“floating bacteria”
planktonic
Ricucci states that with apical periodontitis, :
NO single microorganism is responsible
Progression of RC system infections:
- carious lesion or trauma opens tubules to _____.
- Bacteria inflame the ___.
- ___ may overcome the pulpal defenses and ____ may form in the ____.
- Infection increases in the pulp and ___ begins
- ____ involves the entire ___
- Infection uses “portals of exit” (_______) to invade _____ (_____)
- ____ infection occurs beyond ___ (_____)
- bacterial invasion
- pulp locally
- Inflammation; localized abscesses; coronal pulp
- necrosis
- necrosis; entire root canal system
- apical foramen & lateral canals; periradicular tissues (apical periodontitis)
- periradicular; apex (apical abscess)
During the progression of RC system infections:
What opens the tubules to bacterial invasion?
carious lesion or trauma
During the progression of RC system infections:
What is the significance of a carious lesion or trauma?
opens tubules to bacterial invasion
During the progression of RC system infections:
Initially, where does the inflammation from the bacteria occur?
locally within the pulp
During the progression of RC system infections:
What happens when inflammation overcomes the pulpal defenses?
localized abscesses may form in coronal pulp
During the progression of RC system infections:
Localized abscesses may form in the coronal pulp once what occurs?
once inflammation overcomes the pulpal defenses
During the progression of RC system infections:
Once infection increases in the pulp, what may begin?
necrosis