Lecture 2 -

Question 1

Components of integumentary sytem

Answer 1

skin 
epidermal derivatives(hair, hair follicles, sudoriferous sweat glands, sebacesous oil glands, and nails

Question 2

major functions of integumentary system

pihsee

Answer 2

protective
immunologic
homeostasis
sensory
endocrine
exocrine

Question 3

two principle layers of skin

Answer 3

epidermis

dermis

Question 4

superfical layer of skin

Answer 4

epidermis

Question 5

what kind of tissue is epidermis

Answer 5

keratinized stratified squamous epi

Question 6

epidermis is derived from

Answer 6

ectoderm

Question 7

epidermis and dermis

vascularized or avascular

Answer 7

epidermis- avascular

dermis - highly vascular

Question 8

deep layer of skin

Answer 8

dermis

Question 9

what type of tissue is dermis

Answer 9

connective tissue

Question 10

where is dermis derived from

Answer 10

mesoderm

Question 11

layer deep to skin

Answer 11

hypodermis (subcitansous layer/subcutaneous fasic)

Question 12

what type of tissue is the hypodermis and is it vascular/avascular

Answer 12

adipose tissue

vascularized

Question 13

layers of skin to muscle

Answer 13

epidermis
dermis
hypodermis 
deep tissue
muscle

Question 14

thick vs. thin skin

Answer 14

thick skin- palms and soles of feet, high abrasion areas, no hair, thickest epidermal layer of all skin locations

thin skin - found everywhere else, thinner epidermis, hair follicles present in most places

Question 15

layers/strata of thick and thin skin

layers of epidermis

Answer 15

thick - 5

thin - 4

Question 16

layers/strata of epidermis from deep to superficial

Answer 16

stratum basal 
stratum spinosum
stratum granulosum
stratum lucidum *(thick skin only)
stratum corneum

bad sprinters get leg cramps

Question 17

cells of epidermis 4

Answer 17

keratinocytes - 85%
melanocytes - 5%
Langerhans’ Cells - 2-5%
merkel’s cells - 6-10%

Question 18

cells of the epidermis;

participate in formation of water barrier

Answer 18

keratinocytes

*produce keratins also

Question 19

cells of the epidermis;

pigment-producing cells

Answer 19

melanocytes

Question 20

cells of the epidermis;

antigen-presenting cells of the immune system

Answer 20

langerhans’ cells

Question 21

cells of the epidermis;

mechanoreceptor cells associated with sensory nerve endings

Answer 21

merkel’s cells

Question 22

major structural proteins of epidermis

Answer 22

keratins - produced by keratinocyte in epidermis

Question 23

classified as intermediate filaments, more commonly referred to as tonofilaments

Answer 23

keratins form from keratin filaments

Question 24

keratinocytes participate in formation of epidermal water battier via

Answer 24

production of lamellar bodies

Question 25

tubular/ovoid shaped membrane organelles found in skin containing lipid structures

Answer 25

lamellar bodies

Question 26

single layer of basophilic cells,mitoticall active layer - contains stem cells that give rise to keratinocytes

Answer 26

stratum basal

Question 27

where does production of intermediat (keratin) filaments begin

Answer 27

stratum basal

Question 28

layer of epidermis where keratinocytes exhibit numerous cytoplasmic processes (spines)

Answer 28

stratum spinosum

Question 29

keratinocytes cell processes attached to those of adjacent cells via

Answer 29

desmosomes

Question 30

what contributes to the spiny/prickly appearance of stratum spinosum

Answer 30

cells shrink leaving expanded intercellular space between the spines of the keratinocytes due to histological prep

Question 31

where does the production of keratohyalin granules and lamellar bodies begin

Answer 31

stratum spinosum

Question 32

layer that has tonofilaments grouped into bundles(tonofibrils)

Answer 32

stratum spinosum