Lecture 2 Flashcards
What’s the difference between nucleic acids and nucleotides
Nucleotides are the building blocks that make up nucleic acids
How are nucleotides bonded together
By phospodiester bonds
What are the 2 main nucleic acids
DNA and RNA
What dose DNA carry
Genetic information that is inherited and passed down through cell division
What are the nucleotides
DNA: ATCG
RNA: AUCG
What are nucleotides composed of
Nitrogenous base
Pentose (5 carbon sugar)
Phosphate group
What is a nucleoside
Molecule composed of nitrogenous base linked to 5 carbon sugar (NO PHOSPHATE)
What is a base
Nitrogen containing ring
Which are the pyrimidines
C T U
What are the purines
G A
What sugar in DNA
Deoxyribose
What sugar is in RNA
Ribose
What is the role of the sugar
Holds the nucleotide together
How many phosphate groups can nucleotides have
1 2 or 3
What are the constants
Sugar (ribonucleotides and deoxyribonucleotides)
The phosphate
How many phosphate groups dose a polynucleotide have
One
What’s the variable
The base
What’s the nucleosides matched to the bases
Adenine= adenosine
Guanine=guanosine
Cytosine= cytidine
Uracil= uridine
Thymine= thymidine
What is a nucleoside mono phosphates
A nucleotide
What is the sugar in RNA
Ribose
What are the bases in RNA
A C G U
How many strands in RNA
Single stranded forming bonds with itself
Is there hydrogen bonds in RNA
No
What is the sugar in DNA
Deoxyribose
What is the bases in DNA
A G C T
How many strands in DNA
Double stranded
What direction in the base pair bonds in DNAi
Anti parallel
What bond holds base pairs together
Hydrogen bonding
How many bonds in a AT bond
2
How many bonds are in a GC bond
3
What holds nucleotides together
Covalent phospodiester bonds
Where dose the phosphodiester occur
The OH group on the 3’ Carbon of one nt to the phosphate on the 5’C of the next nt
Is the bonding straight
No it turns to form a helix
What are DNA molecules
2 polynucleotide chains that spiral around an imaginary axis forming a double helix
What dose a purine bind to
Pryrimidine
What do we call the start of the strand
5 prime (5’)
What do we call the end of the strand
3 prime (3’)