Lecture 2 Flashcards
condition or circumstance for which drug has been approved
A particular drug may have multiple indications
Indication
the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration
Off-label indication
Condition that renders treatment improper or undesirable
Contraindication
a representative drug from a class that is used as a point of comparison for related versions of that drug
Learning one drug can allow nurse to extend knowledge to other similar drugs within that class
Prototype Drug
Rate/extent to which active ingredient is absorbed from the drug and then becomes available at site of drug action
Bioavailability
Means by which a drug carries out a therapeutic effect
Mechanism of Action
Describes the mechanism by which the therapeutic effect is achieved
Examples: beta-blockers, diuretics, ACE inhibitors, calcium-channel blockers
Pharmacological Classification
Describes condition for which drug is being given
Examples: antibiotics, antihypertensives, antidepressants, anticoagulants
Therapeutic Classification
Inhibiting blood clotting
Anticoagulants
Lowering blood cholesterol
Antihyperlipidemics
Lowering blood pressure
Antihypertensives
Restoring normal cardiac rhythm
Antidysrhythmics
Treating angina
Antianginals
Lowering plasma volume
Diuretic
Blocking heart calcium channels
Calcium channel blocker
Blocking hormonal activity
Angiotensin-converting enzyme inhibitor
Blocking stress-related activity
Andrenergic antagonist
Dialating peripheral blood vessls
Vasodilator
A drug has only one chemical name
IUPAC
7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-Benzodiazepin-2-one” “diazepam”
NaCl
Chemical names
(International Non-Proprietary Name) lower case and most commonly used by HCPs
Generic names
(proprietary or brand name) Often the original patented name is best known (20 years of exclusive use).
Trade names
drugs with more than one active generic ingredient
New trade name.
Look “active ingredients” list the generic drug names in the product.
Combination drugs
Advil, ibuprofen.
Labelling
By prescription only and provided by a pharmacist, includes:
All prescription drugs
Schedule F: “Pr”
Controlled drugs (Part G)
Narcotic Drugs
Schedule I