Lecture 19: Airway Anatomy (Exam III, Andy's Cards) Flashcards
All of the neurological control of breathing happens in the _________.
Brainstem
(11:44)
Name the 3 parts of the brainstem from superior to inferior.
see below
What is another name for the midbrain?
Mesencephalon
Which part of the brainstem will predominantly regulate the control of respiration?
Medulla
What does PRG stand for?
Pontine Respiratory Group
PRG regulates respiration.
What are the two main parts of the medulla that govern respiration?
- Ventral Respiratory Group (Front)
- Dorsal Respiratory Group (Back)
(14:10)
Where are the Botzinger (BOT) and Pre-Botzinger Complex (Pre-BOT) located?
How does the Botzinger and Pre-Botzinger Complex contribute to respiration?
VRG of the medulla.
Pace the respiratory rate.
Where is the Apneustic Center located?
What does the Apneustic Center stimulate?
What is the result of overstimulation of the Apneustic center?
- Lower Pons
- Apneustic Center stimulates the inspiratory neurons of the DRG in the medulla.
- Overstimulation of the Apneustic Center will result in a prolonged inspiration and brief expiration.
What are two factors that Dr. Schmidt mentioned will control our respiratory drive?
- Planned movement
- Feedback from sensors and blood gas-related products
(18:00)
An increase or decrease in the following blood gas products will result in an increase in respiratory drive.
______ CO2
______ H+
______ O2
______ pH
- ↑ CO2
- ↑ H+
- ↓ O2
- ↓ pH
All these factors will increase respiratory drive.
An increase or decrease in the following blood gas products will result in a decrease in respiratory drive.
______ CO2
______ H+
______ O2
______ pH
- ↓ CO2
- ↓ H+
- ↑ O2
- ↑ pH
All these factors will reduce respiratory drive.
Where are the locations of our chemoreceptors?
- Central (brainstem)
- Periphery
The central chemoreceptors in the brainstem will typically respond to ________, _________, and _______.
- H⁺
- CO₂
- O2
The central chemoreceptors in the brainstem will typically not respond to changes in ______.
- Oxygen
Where are peripheral chemoreceptors located?
- Carotid Body (one on each side of the neck)
- Aortic Bodies (3 or 4 spread across the aortic arch)
Where are the baroreceptors located?
- Carotid Sinus
Chemoreceptors are in the bodies
(20:40)
How do chemoreceptors work?
Blood gas changes drive chemoreceptors (CO2, O2, H+, pH) to either increase or decrease respiratory drive.
When PaO₂ drops below normal (100 mmHg), carotid body nerve impulses will increase, increasing respiratory drive.
High blood flow through the carotid bodies allows them to “see” changes in the body and make adjustments fairly quickly.
What is the primary driver of the peripheral chemoreceptors?
PCO2
↑ PCO2 ,↑ Respiratory Drive
↓ PCO2, ↓ Respiratory Drive
(23:00)
↑ PCO2 will _______ MAP.
increase MAP
Short-term response
(23:30)
How do the aortic bodies relay information back to the medulla?
Vagus Nerve (X)
This will be the same route as the baroreceptors
What pathway does the carotid body take to get back into the brainstem?
Carotid body → Hering’s nerve → Glossopharyngeal Nerve (IX) → Medulla (Nucleus Tractus Solitarius)
(24:30)
The trachea extends from the base of the ________ down to the bifurcation and splitting of the left/right bronchi.
larynx
(25:00)
What is the length of a typical trachea (range)?
By tilting the head back, how much can the trachea elongate?
11 to 13 cm
+2 cm (elongation)
(25:40)
What will happen to the internal diameter of the trachea if there is elongation?
Decreased internal diameter of the trachea.
(26:00)
The width of the trachea is similar to the width of what body part, according to Dr. James Schmidt?
Index Finger
What is the circular structure at the bottom of the larynx attached to the trachea?
Cricoid Cartilage
What cartilages make up the larynx?
How many cartilages make up the larynx?
- Thyroid Cartilage (largest cartilage)
- Epiglottis (large cartilage)
- Cricoid Cartilage (large cartilage)
- Ayrentoids Cartilage (2)
- Cuneiform Cartilage (2)
- Corniculate Cartilage (2)
9 cartilages make up the larynx
What is the length of the right main stem bronchus?
What is the length of the left main stem bronchus?
2 cm (right)
5 cm (left)
Which mainstem is more vertical?
Which mainstem is more horizontal?
The right mainstem is more vertical.
The left mainstem is more horizontal.
(27:30)
How many split points are in each bronchus?
- The right bronchus has 3 split points.
- The left bronchus has 2 splits points.
How many total airway segments are there in the right lung?
How many total airway segments are there in the left lung?
- 10 air segments on the right lung
- 8 airway segments on the left lung
The picture shows 10 airway segments for the left lung, but some segments are fused together.
What type of muscle sits between the tracheal rings?
Smooth Muscle