Lecture 19 Flashcards by Anumeet Kaur | Brainscape

Q

What are the five stages in drug development?

A

Discovery and basic research
Preclinical studies
Clinical testing
Pre-launch activities
Post-marketing studies

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Q

What is the average time period for drug development and how much does it cost?

A

10-12 years and costs > US $800M

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Q

What drugs have been withdrawn from market?

A

Terfenidine- causes cardio-toxicity when coadministered with ketoconazole or grape-fruit juice
Troglitazone- severe hepaptotoxicity
Rofecoxib- Risk of heart attack/stroke

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