Lecture 18: Meiosis Flashcards

1
Q

inhibitors of microtubules

A

taxol, paclitaxel, nocodazole, vinblastine (all toxic )

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2
Q

inhibitors of microfilaments

A

cytochalasin, phallodin

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3
Q

steps of meiosis

A

Interphase (G1, S, G2), Prophase 1, Metaphase 1, Anaphase 1, Telophase 1 and Cytokinesis 1, Prophase 2, Metaphase 2, Anaphase 2, Telophase 2 and Cytokinesis 2

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4
Q

Meiosis I is like

A

the business side of meiosis (separating homologous chromosomes)

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5
Q

Meiosis II is like

A

mitosis (separating sister chromatids)

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6
Q

Prophase I (Meiosis)

A

Centrosome movement along with spindle fiber formation
- Nuclear envelope dissolves
- Chromosomes condense
- Homologous chromosomes pair up and cross over genetic material
- Microtubules attach to kinetochores of each homologous pair (move them to methaphase plate)

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7
Q

Metaphase I (Meiosis)

A

Tetrads are lined up (homologous chromosomes) at the metaphase plate; Spindle fibers attach
- independent assortment

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8
Q

Anaphase I (Meiosis)

A

Homologous chromosomes separate

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9
Q

Telophase I (Meiosis)

A

Cytoplasm divides, 2 daughter cells are formed (nucleus forms), chromosomes condense and nuclear envelope forms

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10
Q

Cytokinesis I

A

cell separates into two cells

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11
Q

Prophase II

A

spindle forms

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12
Q

Metaphase II

A

still 2 chromosomes, 2 chromatids align at metaphase plate

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13
Q

Anaphase II

A

splitting of chromatids (not sisters)

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14
Q

homologous chromosomes

A

same size, contain genes at same location in the chromosome

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15
Q

sister chromatids

A

replicated forms of a chromosome joined together by the centromere

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16
Q

synapsis

A

pairing of replicated homologous chromosomes during prophase I of meiosis

17
Q

crossing over

A

exchange of genetic material between non-sister chromatids during synapsis in meiosis I

18
Q

chiasma

A

area/region where crossing over occurs

19
Q

mitosis vs meiosis similarities

A

both divide at the same time

20
Q

the movement of chromosomes involves

A

microtubules

21
Q

mitosis vs meiosis differences

A

synapsis only occurs in meiosis

22
Q

purpose of meiosis

A

reproduction (gametes)