Lecture 18: Introduction to cardiovascular disease Flashcards
how do we classify CVD?
classify CVD using International Classification of disease 11th revision
large variety of disease in the circulatory system which contributes to CVD
what are the most globally prevalent CVDs?
ischaemic heart disease/coronary heart disease (lack of oxygen in heart)
cerebrovascular disease (stroke) - lack of blood supply in parts of the brain
Hypertension - high blood pressure
what are other important heart conditions?
- rheumatic heart disease, other heart valve disorders
- cardiomyopathy
- abdominal aortic aneurysm
- heart failure
- congenital heart disease
- peripheral vascular disease
- venous thromboembolism
what are the definitions of risk factors? which one is used in public health?
- an aspect of personal behaviour or lifestyle, an environmental exposure, or an inborn or inherited characteristic that, on the basis of scientific evidence, is known the be associated with meaningful health-related conditions (implies there is an association, not cause)
- an attribute or exposure that is associated with an increased probabiity of a specified outcome such as the occurence of a disease. not necessarily a causal factor: may be a risk marker (might mean a higher risk of heart disease, but not a cause of heart attack)
- a determinant that can be modified by intervention, therby reducing the probability of occurence of disease or other outcomes. it may be reffered to as a modifiable risk factor and logically must be a cause of the disease. (use this definition in the course)
what are the non-modifiable risk factors for cardiovascular disease?
- age
- sex
- family history premature CVD
- personal history of CVD
- atrial fibrillation/conduction disorders
what are the modifiable risk factors in primary care?
- smoking
- elevated blood pressure
- diabetes
- metabolic syndrome/impaired CHO metabolism/insulin resistance
- dyslipidaemia
- obesity
- physical activity (sedentary behaviour)
- poor diet
- inflammation
- gender?????
what are the modifiable risk factors of CVD in public health?
- smoking
- elevated blood pressure
- diabetes
- metabolic syndrome/impaired CHO metabolism/insulin resistance
- dyslipidaemia
- obesity
- physical activity (sedentary behaviour)
- poor diet
- inflammation
- gender?????
- low socioeconomic status - especially in childhood
- depression, social isolation and lack of social support
what is atherosclerosis?
- happens in arteries and primary pathological events that happens in CVD, build up of fatty depositions in the inner walls
- risk factors: cholesterol, BP, inflammation combine to form atherosclerosis
what is IHD, CHD, CAD and what can it lead to?
ischaemic heart disease, coronary heart disease and coronary artery disease
atherosclerosis in the vessel wall lead to narrowing of BV and reduces nutrients being delivered to heart wall
- can lead to angine (chest pain) and acute heart attack (myocardial infarction)
what are the 2 types of cerebrovascular disease/stroke?
- ischaemic (blockage of blood vessels)
- haemorrhagic (rupture of blood vessels)
what is elevated blood pressure?
- increase pressure in arteries
Hypertension
Systolic, diastolic blood pressure (mmHg)
important risk factor but can lead to direct problems
what is systolic and diastolic BP?
systolic
- occurs when the ventricles contract to pump blood into the circulatory system
diastolic
- occurs when the ventricles relex and the heart refills with blood before the next contraction
what is congenital heart disease?
many different types
e.g. abnormailities of valves, heart muscle, septum (atrial/ventricular), arrangement of major blood vessels
- important for child health
what is rheumatic heart disease?
Rheumatic fever - autoimmune reaction to throat infection
Rheumatic heart disease - repeated episodes of RF affects heart valves
High gradient of deprivation (e.g. Maori, Pacific, Indigenous australians)
what is heart failure?
heart not pumping well
- but is NOT a heart attack
May be due to:
- ischaemic heart disease
- hypertension
- cardiomyopathy
- heart valve abnormalities
- diabetes
- excess alcohol
- viral infection of heart
- thyroid disease