Lecture 15 Flashcards
Ketone with…..LDA,RMGX,NAOH,CO3
Complete enolate
NA
PE..WITH SC
NO
Ester with…..LDA,RMGX,NAOH,CO3
CE
NS
NS+PE AND SC
NO
ACYL CHLORIDE WITH…LDA,RMGX,NAOH,NET3
Ns
NS
NS
REQUIRED MASKING
ALDEHYDE WITH……LDA,RMGX,NAOH,CO3
PE+SC…..NA
NA
PE+SC
NO
Reaction of cyanide with….lda,rmgx,naoh
CE
NA
PE
Carboxylic acid, amide = lDA OR NAOH
Carboxylic acid +acidic enolization =
Strong base like lDA,but not NAOH
Racemization, selfisomerization
How many lDA requrie for alkylation of aceticacid
The formula is no.of acidic alpha hydrogen +1
Acidity order
Reactivity order
A. Oh
B. NH
C. CH
Acidity order….a>b>c
Reactivity order…..c>b>a
Name of non nucleophilic base
Lda ki puri family
Na,k
R3N,tbuo-k+,co32-
Nucleophilic bases name
GR
NH3,NH2-
OH-/OR-