Alkylation

Question 1

Alkylation
Acidic. 2 step
Basic1 step

Question 2

Regioselective which one

Answer 2

So only one product will be possible in acidic enolization but base can make either stable or unstable enolate

Question 3

Polyalkylation occur with which base

Answer 3

NaH,kH
Only when they are given in moren than 1equivalent

Question 4

Agr kh ki jagah NaOH use Kar ke Mel de to

Answer 4

MeOH
Use phase transfer catalyst

Question 5

LICA IS SIMILAR TO

Answer 5

LDA

Question 6

Alkylation of aldehyde Can be occur by

Answer 6

Via examine R2NH/H+
VIA aza enolatevRNH2/H+

Question 7

In alkylation of aldehyde which pathway Wil be preferred

Answer 7

Examine pathway
Because of stable product with more electrophilic centre

Question 8

The centre of nitrogen is soft or hard

Answer 8

Soft

Question 9

For alkylation in carbonyl compound the competition between the
And in examine the competition between the

Answer 9

O- C

N* * lp. C- that’s why alkylation can be possible in both the centre

Question 10

When the alkylation undergoes through N alkylation or C alkylation

Answer 10

Allyl ,benzyl,Halogenation carbonyl give C alkylation
And methy halide primary or secondary give N alkylation