Lecture 15 & 16 Flashcards

1
Q

What are the 3 types of muscle

A

skeletal
cardiac
smooth

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2
Q

striated muscle, voluntary movement, contraction regulated by the somatic n.s.

A

skeletal

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3
Q

striated muscle in heart, contraction regulated by the autonomic n.s.

A

cardiac

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4
Q

muscle in blood vessels, visceral tissues, contraction regulated by autonomic n.s.

A

smooth muscle

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5
Q

3 layers of connective tissue membranes

A

epimysium
perimysium
endomysium

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6
Q

layer of cells encasing entire muscle

A

epimysium

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7
Q

layer of cells encasing a bundle of muscle fibers

A

perimysium

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8
Q

layer of cells encasing individual muscle fibers

A

endomysium

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9
Q

cell membrane of individual muscle fibers

repeating unit that forms the myofibrils

A

sarcolemma

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10
Q

strand of interacting proteins (actin and myosin) that runs parallel to the length of the muscle

A

myofibrils

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11
Q

individual sacromeres separated by

A

z-disks

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12
Q

myofibrils are composed of what myofilaments (proteins)

A

thick (myosin)

thin ( 2 actin chains, trooponin, tropomyosin)

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13
Q

during muscle contraction, why does the sarcomere shorten?

A

there is a greater degree of overlap btwn the thick and thin filaments - NO CHANGES IN LENGTH

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14
Q

Muscle contraction needs what 3 things

A

ATP, nerve impulse (acetylcholine), and calcium

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15
Q

ATP is needed to do what in the sliding filament theory

A

separate actin from myosin from the previous contraction cycle

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16
Q

Myosin ATPase cleaves ATP to

A

ADP = Pi

17
Q

attached to actin filaments and tropomysin, binds calcium

A

troponin

18
Q

Ca2+ enters the cytoplasm due to

A

nerve stimulation

19
Q

powerstroke

A

when thick and thin filaments slide over each other

20
Q

smooth muscle contraction is dependent on

A

Ca2+ concentrations

21
Q

single unit smooth muscle

A

“joined” by gap junctions
coordinated contraction
GIT, small blood vessels

22
Q

multi-unit

A

cells as individual units, more direct neural control,

eyes, arteries, hair, erectors

23
Q

cardiac cells are joined together with

A

intercalated disks

24
Q

2 types of intercalated disks

A

gap junction and desmosomes

25
Q

signals form one cell can move into another

A

gap junctions

26
Q

hold cells tightly together

A

desmosomes

27
Q

relationship between membrane depolarization and contraction

A

excitation-contraction coupling

28
Q

releases Ca2+ upon membrane

A

sarcoplasmic reticulum

29
Q

allows membrane depolarization deep into the muscle fiber

A

T-tubles

30
Q

2 voltage gated calcium channels

A

T-tubules: DHRPs

Sarcoplasmic reticulum: RyR

31
Q

distance btwn insertion (end of the muscle that attaches to the freely moving bone) and origin (end of muscle that attaches to the “fixed” bone in the joint) shortens

A

whole-muscle contraction

32
Q

decreases joint angle

A

flexion

33
Q

increases joint angle

A

extension

34
Q

3 types of muscle fibers

A

1) slow oxidative
2) fast oxidative/glycolytic
3) fast glycolytic