Lecture 14 - urinary incontinence Flashcards

1
Q

Lower motor neuron lesion

A

E.g. cauda equina

  • PS affected at S2,3,4
  • can’t void
  • reduced perianal sensation
  • lax anal tone
  • Low detrusor pressure as can’t contract
  • Large residual urine - overflow incontinence
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2
Q

Upper motor neurone lesion

A

The PS aren’t inhibited as much

  • Detrusor sphincter dyssynergia
  • High pressure detrusor contractions
  • Poor coordination with sphincters

Detrusor muscle hypertrophy - dilates ureter and kidneys due to back pressure

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3
Q

Stress incontinence

A

Involuntary leaking on effort or exertion as well as:

  • cough
  • laugh
  • sneezing
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4
Q

Urgency incontinence

A

Involuntary leaking associated with immediate urgency - can’t hold it in

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5
Q

Mixed urinary incontinence

A

Involuntary leaking associated with urgency, exertion, effort and sneezing or coughing

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6
Q

Overflow incontinence

A

Involuntary leaking due to

  • lower urinary tract lesion
  • chronic retentionq
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7
Q

Most common type of incontinence

A

Stress incontinence

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8
Q

Risk factors for incontinence

A
Family predisposition
Pregnancy and vaginal delivery
Pelvic prolapse
Menopause - decreased oestrogen so less anal tone
Obesity
Age
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9
Q

Examination for incontinence

A

BMI
Abdominal exam - palpable bladder in chronic retention

Male: DRE

Females:
- external genitalia stress test

  • vaginal exam - atrophic after menopause
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10
Q

Investigations for incontinence

A

Urine dipstick:

  • UTI
  • haematuria
  • proteinuria
  • glucosuria

Non invasive urodynamics

  • voiding patterns - bladder diary
  • frequency - volume chart
  • post micturition residual volume

Optional:

  • invasive urodynamics - pressure flow studies +/- video
  • pad tests
  • cystoscopy - if haematuria
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11
Q

Pressure flow studies

A

Detrusor pressure and function
Residual volume
Abdominal pressure
Bladder pressure

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12
Q

Detrusor pressure

A

= Total pressure - abdominal pressure

Coughing increases abdominal pressure but destrusor pressure stays the same

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13
Q

Management of incontinence

A
Modify fluid intake
Weight loss 
Stop smoking
Decrease caffeine intake
Routine voiding schedule every 4 hours
Avoid constipation

Pelvic floor muscle training - 8 contractions 3x a day for atleast 3 months

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14
Q

Failed conservative management

A

Indwelling catheter
Sheath device
Incontinence pads

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15
Q

Pharmological management

A

Duloxetine

= combined noradrenaline and serotonin uptake inhibitor

  • Increased activity in striated sphincter during filling phase
  • Not first line as feel nauseous
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16
Q

Surgery for incontinence

A

Females:

  • sling
  • Vaginal tapes
  • suspension

Temporary - intramural bulking agents of urethra

Males:

  • artificial urinary sphincter - gold standard
  • Male sling procedure
17
Q

Retropubic suspension procedure

A

Correct anatomical position of proximal urethra and improve urethral support

18
Q

Bladder training

A

Void every hour during the day without voiding in between

Intervals increased by 15 - 30 mins per week until 2 -3 hours reached

  • At least 6 weeks duration
19
Q

Anticholinergics

A

[don’t give to patients with glaucoma]

Acts on m2, m3 muscarinic receptors

  • Decreases parasympathetic stimulation
20
Q

Beta 3 adrenoreceptor agonist

A

Increases bladder’s capacity to store urine as relaxes smooth muscle of bladder

21
Q

Botulinum toxin

A

Intravesicular injection

Inhibits release of Ach at presynaptic neuromuscular junctions - flaccid paralysis

Can causes retention

22
Q

Enuresis in children

A

Involuntary bedwetting during sleep at least 2x a week in children above 5 with no CNS defects

23
Q

Primary enuresis

A

Never achieved sustained continence at night

24
Q

Secondary enuresis

A

Restarted bedwetting having been dry at night for more than 6 months

25
Q

Management of enuresis

A

Primary:

  • reassurance and positive reward system
  • Desmopressin - reduce urination at night

Secondary:
treat underlying cause e.g. UTI, diabetes or neurological problems