Lecture 13 (Apoptosis in development & diseases)

Question 1

Which of the following organelles plays a pivotal role in Apoptosis:

Answer 1

Mitochondria

Question 2

The characteristic feature of apoptosis on light microscopy is:

Answer 2

Nuclear compaction

Question 3

Which of the following has a direct role in apoptosis:

Answer 3

Cytochrome C

Question 4

Caspases are involved in:

Answer 4

Apoptosis

Question 5

All of the following are features of Apoptosis, except:

Answer 5

Cellular swelling

Question 6

This is an extracellular messenger of apoptosis:

Answer 6

Tumor necrosis factor

Question 7

This is concerned with the intrinsic pathway of apoptosis:

Answer 7

Cytochrome c

Question 8

Apoptotic bodies can be recognized with the presence of these on the surface:

Answer 8

Phosphatidylserine

Question 9

Apoptotic cells detach due to the inactivation of

Answer 9

FAK

Question 10

Shrinking of nucleus is caused when this is inactivates:

Answer 10

Lamin

Question 11

This can stimulate cytochrome release from mitochondria:

Answer 11

Bid

Question 12

This cannot be killed by apoptosis

Answer 12

Cancer cells

Question 13

The special enzymes are released during necrosis from

Answer 13

Lysosomes

Question 14

The causes of necrosis includes:

Answer 14

Injury, cancer and infection