Lecture 12- Enzyme linked Receptor Flashcards
1
Q
How are enzyme-linked receptors different from G-protein linked receptors?
A
Enzyme-linked receptors have their own enzymatic activity, and do not work through Trimeric G proteins.
2
Q
What do receptor tyrosine kinases undergo?
A
Dimerization and autophosphorylation.
3
Q
What is dimerizarion?
A
When two receptors phosphorylation each other on multiple tyrosines.
4
Q
Two receptors phosphorylating each other on multiple kinases is what?
A
Dimerization.
5
Q
What is the first step in relaying the signal to the cell interior for receptor tyrosine kinases?
A
Dimerization.
6
Q
What class of enzyme-linked receptor will we focus on?
A
Receptor tyrosine kinase.
7
Q
What do SH2 domains do?
A
They bind to phosphorylase do tyrosines.
8
Q
What do SH3 domains do?
A
They mediate interactions with other proteins.
