Lecture 12 Flashcards
Hydrogen pairs with their electrons are delivered to ETC carrier molecules by
the coenzymes NAD and FAD (their reduced forms)
The electrons flow from one carrier molecule to another in a series of
oxidation and reduction reactions
In aerobic respiration what is the
final hydrogen/electron acceptor
oxygen
As these reactions proceed ATP is generated and released incrementally by a process known as
chemiosmosis
cytochromes
Many of the ETC intermediates are iron containing
compounds known as cytochromes
For every 2H (hydrogen pair) delivered to the ETC on NAD how many ATPs are manufactured
3 ATPs are manufactured
For every 2H delivered to the ETC on FAD on many ATPs are manufactured
2 ATPs are manufactured
The vast majority of the cells ATPs are manufactured in
the ETC
The ATP is produced here by a process known as
oxidative phosphorylation
ETC is sometimes referred to as
the Respiratory Chain or the Cytochrome Chain.
In anaerobic respiration the final hydrogen/electron acceptor is
In anaerobic respiration there are inorganic final hydrogen/electron acceptors other than oxygen that
are driving the oxidation and reduction reactions
Why are there fewer ATP generated in anaerobic
However, since the pull of these other inorganic acceptors is less than oxygen, there are fewer ATP’s generated.
Glycolysis total ATP
2 ATPs by substrate level phosphorylation
6 ATPs by oxidative phosphorylation in ETC. (2 NAD each with a 2H are produced) Note, each 2H carried
to ETC on NAD yields 3 ATPs. 2 X 3 = 6
Intermediate or Preparatory Step total ATP
6 ATPs by oxidative phosphorylation in ETC. (An NAD with a 2H is produced for each pyruvic acid that is
converted into an acetyl group. Two acetyl groups are made from each glucose, as two pyruvic acids are
made from each glucose).
Krebs Cycle total ATP
2 ATPs by substrate level phosphorylation
18 ATPs by oxidative phosphorylation in ETC. (6 2H are delivered to ETC on NAD per glucose).
4 ATPs by oxidative phosphorylation in ETC. (2 2H are delivered to ETC on FAD per glucose).