Lecture 11- Somatic Sensory System Flashcards

1
Q

Give a general overview of the sensory pathway from receptor endings (dermatome)

A

stimuli–> dorsal root ganglion –> pain and temp decussates at level of entry/ mechanosensory fibres travel up through spinal cord to cuneate (upper body)/ gracile (lower body) nuclei then decussate at medial lemniscus in medulla –> up through medulla –> midbrain –> thalamus –> somatosensory cortex of cerebrum

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2
Q

what is sensory transduction?

A

where the energy of a stimulus is converted to an electrical signal

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3
Q

what are the 2 types of receptors?

A

rapidly adapting
slowly adapting

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4
Q

what’s the difference between rapidly adapting and slowly adapting receptors?

A

rapidly adapting are transient, firing maximally in immediate response to stimulus briefly
slowly adapting are tonic and fire as long as stimulus is present

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5
Q

what are the 5 receptors found in the skin for tactile stimulation?

A
  • meissner corpuscle
  • pacinian corpuscle
  • ruffini’s corpuscle
  • merkel’s disc
  • free nerve endings
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6
Q

describe Meissner corpuscles

A
  • rapidly adapting
  • most common in smooth/hairless skin
  • 40% hand innervation
  • detects texture moving across skin- useful in detecting object slippage/grip
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7
Q

describe Pacinian corpuscles

A
  • rapidly adapting
  • more sensitive that Meissner- fine textures
  • 15% hand innervation
  • tickle/vibration sensation
  • skilled tool use
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8
Q

Describe Ruffini’s Corpuscles

A
  • slowly adapting
  • 20% receptors in hand
    -unknown function but linked to proprioception
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9
Q

Describe Merkel’s Discs

A
  • slowly adapting
  • 25% receptors in hand
  • dense in fingertips
  • stimulation produces light pressure sensation
  • detection of shape/edges/rough texture- braille reading
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10
Q

Describe free nerve endings

A

pain and temp sensation

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11
Q

Why is it useful to understand these receptors?

A

developing artificial systems and bioimplants

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12
Q

name 3 areas of the body which have the greatest 2-point discrimination threshold

A

hands, face, feet

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13
Q

name 3 areas of the body that have the lowest 2-point discrimination threshold

A

legs, arms, back

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14
Q

what determines 2-point discrimination threshold?

A

the density of receptors and the size of their receptive field

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15
Q

what are the 2 main types of proprioceptors?

A

muscle spindles
golgi tendon organs

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16
Q

what do muscle spindles do?

A

signal muscle length

17
Q

what do golgi tendon organs do?

A

signal changes in muscle tension

18
Q

what does the number of muscle spindles reflect?

A

how fine the control of each muscle is

19
Q

where in the body has the highest density of muscle spindles?

A

oculomotor muscles

20
Q

what are the 2 types of muscle spindles and what do they indicate?

A

group 1- info about dynamic movement
group 2- info about static positions of limbs

21
Q

do golgi tendon organs respond to passive stretch?

A

no, only active contraction

22
Q

what are the 3 key somatic sensory pathways?

A
  • dorsal column medial lemniscus
  • trigeminal system
  • spinothalamic
23
Q

generally what does the dorsal column medial lemniscus pathway detect?

A

upper and lower body sensation

24
Q

generally what does the trigeminal system pathway detect?

A

face sensation

25
generally what does the spinothalamic tract detect?
pain and temp
26
describe the pathway of the dorsal column medial lemniscus pathway
mechanosensory receptor--> dorsal root ganglion--> up spinal cord--> upper body cuneate/lower body gracile tracts in medulla--> cuneate and gracile nuclei in medulla--> decussates in medulla--> through medial lemniscus of medulla/ pons/ midbrain --> ventral posterior lateral (VPL) nucleus of thalamus --> somatosensory cortex of cerebrum
27
which dermatomes have more overlap, touch or pain?
touch
28
describe the pathway of the trigeminal tract
mechanosensory receptors in face--> trigeminal ganglion--> decussates at medulla to enter medial lemniscus--> up through pons and midbrain--> ventral posterior medial nucleus (VPM) --> somatosensory cortex
29
describe the structure of the primary somatosensory cortex
it's divided into 3a, 3b, 1 and 2 areas anterior to posterior 3a- proprioception 3b+1- cutaneous stimuli 2- proprioceptors and tactile stimuli
30
describe Albrecht et al's study into plasticity
focussed laser to induce stroke in forelimb cortical region, found after 90 minutes there was a redistribution of forelimb cortical sensation to hindlimb region
31
Describe Frostig's 2012 study into mechanism of rat stroke plasticity
MCA filament occlusion model to cause permanent stroke, if whiskers were tickled soon after stroke, cortex was restored, if tickled 3 hours after, make damage worse thought to be ACA providing some compensatory blood to region if stimulated