Lecture 11- Somatic Sensory System Flashcards

1
Q

Give a general overview of the sensory pathway from receptor endings (dermatome)

A

stimuli–> dorsal root ganglion –> pain and temp decussates at level of entry/ mechanosensory fibres travel up through spinal cord to cuneate (upper body)/ gracile (lower body) nuclei then decussate at medial lemniscus in medulla –> up through medulla –> midbrain –> thalamus –> somatosensory cortex of cerebrum

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2
Q

what is sensory transduction?

A

where the energy of a stimulus is converted to an electrical signal

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3
Q

what are the 2 types of receptors?

A

rapidly adapting
slowly adapting

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4
Q

what’s the difference between rapidly adapting and slowly adapting receptors?

A

rapidly adapting are transient, firing maximally in immediate response to stimulus briefly
slowly adapting are tonic and fire as long as stimulus is present

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5
Q

what are the 5 receptors found in the skin for tactile stimulation?

A
  • meissner corpuscle
  • pacinian corpuscle
  • ruffini’s corpuscle
  • merkel’s disc
  • free nerve endings
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6
Q

describe Meissner corpuscles

A
  • rapidly adapting
  • most common in smooth/hairless skin
  • 40% hand innervation
  • detects texture moving across skin- useful in detecting object slippage/grip
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7
Q

describe Pacinian corpuscles

A
  • rapidly adapting
  • more sensitive that Meissner- fine textures
  • 15% hand innervation
  • tickle/vibration sensation
  • skilled tool use
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8
Q

Describe Ruffini’s Corpuscles

A
  • slowly adapting
  • 20% receptors in hand
    -unknown function but linked to proprioception
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9
Q

Describe Merkel’s Discs

A
  • slowly adapting
  • 25% receptors in hand
  • dense in fingertips
  • stimulation produces light pressure sensation
  • detection of shape/edges/rough texture- braille reading
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10
Q

Describe free nerve endings

A

pain and temp sensation

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11
Q

Why is it useful to understand these receptors?

A

developing artificial systems and bioimplants

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12
Q

name 3 areas of the body which have the greatest 2-point discrimination threshold

A

hands, face, feet

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13
Q

name 3 areas of the body that have the lowest 2-point discrimination threshold

A

legs, arms, back

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14
Q

what determines 2-point discrimination threshold?

A

the density of receptors and the size of their receptive field

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15
Q

what are the 2 main types of proprioceptors?

A

muscle spindles
golgi tendon organs

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16
Q

what do muscle spindles do?

A

signal muscle length

17
Q

what do golgi tendon organs do?

A

signal changes in muscle tension

18
Q

what does the number of muscle spindles reflect?

A

how fine the control of each muscle is

19
Q

where in the body has the highest density of muscle spindles?

A

oculomotor muscles

20
Q

what are the 2 types of muscle spindles and what do they indicate?

A

group 1- info about dynamic movement
group 2- info about static positions of limbs

21
Q

do golgi tendon organs respond to passive stretch?

A

no, only active contraction

22
Q

what are the 3 key somatic sensory pathways?

A
  • dorsal column medial lemniscus
  • trigeminal system
  • spinothalamic
23
Q

generally what does the dorsal column medial lemniscus pathway detect?

A

upper and lower body sensation

24
Q

generally what does the trigeminal system pathway detect?

A

face sensation

25
Q

generally what does the spinothalamic tract detect?

A

pain and temp

26
Q

describe the pathway of the dorsal column medial lemniscus pathway

A

mechanosensory receptor–> dorsal root ganglion–> up spinal cord–> upper body cuneate/lower body gracile tracts in medulla–> cuneate and gracile nuclei in medulla–> decussates in medulla–> through medial lemniscus of medulla/ pons/ midbrain –> ventral posterior lateral (VPL) nucleus of thalamus –> somatosensory cortex of cerebrum

27
Q

which dermatomes have more overlap, touch or pain?

A

touch

28
Q

describe the pathway of the trigeminal tract

A

mechanosensory receptors in face–> trigeminal ganglion–> decussates at medulla to enter medial lemniscus–> up through pons and midbrain–> ventral posterior medial nucleus (VPM) –> somatosensory cortex

29
Q

describe the structure of the primary somatosensory cortex

A

it’s divided into 3a, 3b, 1 and 2 areas anterior to posterior
3a- proprioception
3b+1- cutaneous stimuli
2- proprioceptors and tactile stimuli

30
Q

describe Albrecht et al’s study into plasticity

A

focussed laser to induce stroke in forelimb cortical region, found after 90 minutes there was a redistribution of forelimb cortical sensation to hindlimb region

31
Q

Describe Frostig’s 2012 study into mechanism of rat stroke plasticity

A

MCA filament occlusion model to cause permanent stroke, if whiskers were tickled soon after stroke, cortex was restored, if tickled 3 hours after, make damage worse
thought to be ACA providing some compensatory blood to region if stimulated