Lecture 11 - small intestine Flashcards

1
Q

When do we get rumbling or a series of peristaltic waves?

A

men - 91 mins

women - 89 mins

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2
Q

what is rumbling caused by?

A

It is caused by turbulent flow and so water that is falling on air causes bubbles and sounds

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3
Q

where does most of the absorption of nutrients occur?

A

in the small intestine

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4
Q

where does most of the digestion occur?

A

before the small intestine

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5
Q

When does chyme move into the small intestine?

A

0-3 hours after entering the stomach

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6
Q

how long does it take for chyme to move through the small intestine?

A

1-6 hr because it is 6 m

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7
Q

where is digested food absorbed?

A

into the blood stream and lymphatic system

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8
Q

what occurs in the duodenum?

A

absorption and digestion

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9
Q

what occurs in the jejunum?

A

absorption and digestion

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10
Q

what occurs in the ileum?

A

absorption

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11
Q

what is the conduction rate in the small intestine?

A

1 cm/min

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12
Q

what is the small intestine influenced by in regards to the nervous system and hormones?

A
  • enteric nervous system

- hormones: gastrin, cholecystokinin, secretin

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13
Q

SA in small intestine? from just cylinder to circular folds to villi to microvilli

A

cylinder - relative SA: 1 and actual SA (m2): 0.33
circular folds- 3 and 1
villi - 30 and 10
microvilli - 600 and 200 m2

3 fold to 10 fold to 20 fold
Surface area of small intestine is 200 m2
total of 600 fold increase

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14
Q

Organisation of gut wall?

A

lining the lumen - absorptive cells
below - neurral and muscular components

blood and lynph vasculature is abundant to transport absorbed nutrients

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15
Q

by projecting into the lumen, the villi ….. SA for …… of nutrients

A
  • increases

- absorption

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16
Q

Microvilli ….. the villi to …. SA

A
  • fringe

- increase

17
Q

what is digestion in the small intestine aided by?

A

it is aided by exymes and fluid that is secreted by the pancreas

18
Q

what doe exocrine cells of the pancreas secrete?

A

digestive enzyme?

19
Q

what do duct cells secrete?

A

bicarbonate

20
Q

how are secretions from the liver and pancreas delivered to the duodenum?

A

through the sphincter of oddi

21
Q

What do acini and duct cells secrete?

A

acini - secrete enzymes

duct - secrete bicarbonate

22
Q

what are acini and duct cells stimulated by?

A

acini - CCK and ACh

duct - secretin

23
Q

what is pancreatitis?

A

inflammation of the pancreas

24
Q

where does intestinal fluid come from?

A

it comes from the pancreas and liver

25
what does intestinal fluid contain?
pancreas: -secretion of NaHCO3 solution - CL/HCO3 antiport co transporter on apical membrane, HCO3 enters pancreatic duct and Na+ is secreted through cell junctions Liver: -NaHCO3 secreted by liver (bile)
26
what happens to the small intestine when there is an increase in acid present int he stomach?
1. ) increase presence of acid in the stomach 2. ) small intestine secretes secretin 3. ) Increase in plasma secretin 4. ) pancreas increases bicarbonate secretion 5. ) increase flow of bicarbonate into the small intestine 6. ) small intestine neutralises intestinal acid
27
secretin receptors found in the ..... respond to increase acid (and so release of secretin from small intestine) with additional ..... delivery which causes ..... and ....
- pancreas - bicarbonate - gastric motility and secretion are inhibited
28
what is the function of deoxyribonuclease?
it is protection because we dont want viral DNA in the blood stream so it breaks it down
29
How much carbs do we use a day and how much does the brain use a day?
- we use 250g/day | - brain - 125 g/day
30
how much carbs do we eat a day?
250 g/day
31
what are some challenges in the absorption of carbs?
glucose, fructose and galactose are polar molecules so cant cross membranes except with transporters
32
What are some transporters of glucose?
GLUT 2 and SGLT 1
33
What kind of carbs are absorbed in the body?
only monosaccharides are absorbed so disaccharides and polysaccharides must be digested before they are absorbed.