Lecture 11

Question 1

building block of actin is ?

Answer 1

G-actin (globular)

Question 2

G-actin polymerizes to give rise to ?

Answer 2

F-actin (filamentous)

Question 3

F-actin

Answer 3

polar filament with barbed (plus) end and pointed (minus) end

Question 4

G-actin concentration during in vitro actin polymerization

Answer 4

• above CC the plus-end grows faster than the minus-end

- below CC the plus-end shrinks faster than the minus-end

Question 5

When does treadmilling occur during actin polymerization ?

Answer 5

steady state (Kd affinity on both ends must be equal)