Lecture 10a: Physical and Brain Development in Adolescence Flashcards
What happens to grey and white matter during middle childhood?
During middle childhood, developments in the brain include changes to white and gray matter volume, growth in the complexity of neural networks, and increased coordination across regions of the brain.
What happens to white matter?
White matter volume increases linearly throughout middle childhood and adolescence, reflecting the myelination of axons
Recall that myelin is the fatty white sheath that surrounds axons.
The growth in myelin helps strengthen brain connections by allowing faster transmission of neural signals.
What happens to grey matter?
Grey matter increases in childhood and then decreases in adolescence, reflecting the pruning of unused synapses.
Peaks to gray matter volume occur in different regions of the brain at different times in development.
How can we appreciate adolescent thinking?
To fully appreciate adolescent thinking and decision making, it’s helpful to consider the asymmetrical maturity of different brain regions across development. Notably, by adolescence, the prefrontal cortex is relatively immature in its development compared to the more complete maturation of the limbic system
What is the limbic system?
The highly active adolescent limbic system which includes the hippocampus, amygdala, and cingulate gyrus, among other structures is packed with neurons that are involved in motivation and emotions.
Simplified; The limbic system is a group of interconnected brain structures that help regulate your emotions and behavior
What is Puberty?
Period of lifespan in which individual becomes capable of sexual reproduction
What are the 3 chief physical manifestations?
- Rapid acceleration in growth (height, weight)
- Development of primary sex characteristics (gonads)
- Development of secondary sex characteristics
What is the Endocrine System
Produces, circulates, and regulates hormone levels in the body
- Hormones
- Glands
- Gonadotropin-releasing hormone (GnRH) neurons
What is the Hypothalamic-Pituitary-Gonads “HPG Axis”
Reproduction and fertility are regulated via hormones of the hypothalamic-pituitary-gonadal (HPG) axis.
**Controls production of
androgens and estrogens by
gonads
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What are Primary sex characteristics
Primary sex characteristics are associated with the reproductive organs, ovaries, uterus, and vagina in girls, and penis, scrotum, and testes in boys.
Primary sex changes result in the production of ova in girls and sperm in boys, which enable reproduction.
What are secondary sex characteristics?
Secondary sex characteristics include observable body changes such as a growth spurt, pubic hair, breasts in girls, and facial hair and changes to voice in boys.
What Triggers Puberty?
Puberty begins when several different signals – genetic, environmental – instruct the brain to change the “set
point” of the HPG axis
What signals the HPG axis to change the set point?
Increase in brain chemical called “kisspeptin” – initiates increased
secretion of GnRH from hypothalamus
[Gonadotropin hormone-releasing hormone (GnRH)]
Hypothalamus becomes less sensitive to androgens/estrogens
What products kisspeptin?
Leptin (protein produced by fat cells) stimulates production of kisspeptin
What are the 3 chief physical changes during Somatic Development?
- Adolescent growth spurt
- Development of primary sex characteristics (gonads)
- Development of secondary sex characteristics (breasts, body hair)