Lecture 10 - Palliative Care Flashcards

1
Q

8 Domains of Quality Palliative care

A
  1. structure and process of care
  2. physical aspects of care
  3. psychological and psychiatric aspects of care
  4. social aspects of care
  5. spiritual, religious and existential aspects of care
  6. cultural aspects of care
  7. care of the pt at the end of life
  8. ethical and legal aspects of care
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2
Q

For hospice, life expectance has to be under….

A

6 month

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3
Q

Types of pain

A

Nociceptive
Neuropathic
Existential
Mixed

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4
Q

How to asses pain

A

FACES = pictures
Numerical Rating Scale
PQRST

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5
Q

Morphine Dose Adjustments

A

Renal: avoid in severe impairment
Hepatic: favorable w/ monitoring, inc dosing interval if severe impairment

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6
Q

Oxycodone Dose Adjustments

A

Renal: favorable with monitoring
Hepatic: cation n monitor, reduce dose 50% or inc dosing interval if severe

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7
Q

Hydromorphone Dose Adjustments

A

Renal: favorable with monitoring
Hepatic: caution n monitor, reduce dose 50% or inc dosing interval if severe

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8
Q

Fentanyl Dose Adjustments

A

Renal: preferred opioid in impairment
Hepatic: avoid in severe impairment, reduce doe 50% if mild-moderate

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9
Q

Methadone Dose Adjustments

A

Renal: preferred opioid in impairment
Hepatic: Avoid liver failure or severe impairment

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10
Q

Adverse effects opioids

A

constipation
Sedation
Respiratory depression
N/V
Pruritus
Hallucinations
Confusion/delirium
Myoclonus

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11
Q

Morphine dosing

A

10mg IV = 30mg Oral

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12
Q

Hydrocone to morphine

A

30mg Oral = 30mg Morphine Oral

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13
Q

Hydromorphone dosing equiv

A

1.5mg IV = 7.5mg Oral (= 30mg morphine oral)

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14
Q

Oxycodone to morphine equiv

A

20mg Oral = 30mg Oral morphine

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15
Q

Oxymorphone Dosing equiv

A

1mg IV = 10mg Oral (= 30mg Morphine oral)

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16
Q

Daily dosage 60-134mg Morphine Fentanyl equiv

A

25mcg/h patch

17
Q

Daily dosage 135-224mg Morphine Fentanyl equiv

A

50mcg/h patch

18
Q

Daily dosage 225-314mg Morphine Fentanyl equiv

A

75mcg/h patch

19
Q

Daily dosage 315-404mg Morphine Fentanyl equiv

20
Q

Going from Fentanyl patch to morphine

A
  1. remove patch
  2. for 1-12hrs after, use PRN opioid only
  3. at 12hrs, start new scheduled opioid at 50% of dose
  4. at 24hrs, inc new scheduled opioid at 100% of dose
21
Q

If taking methadone w/ enzyme inducer then….

A

might need to inc methadone, use rescue opioid

22
Q

If taking methadone w/ enzyme inhibitor then….

A

reduce calc dose of methadone by 25% or more, encourage use of rescue opioid

23
Q

Appropriate Methadone Candidates

A

True morphine allergy
Sig renal impairment
Neuropathic pain
Opioid-induced adv effects
Pain refractory to other opioids or uncontrolled pain
Cost is an issue
LA opioid preferred
any opioid req patient

24
Q

Supplemental opioids

A

want to use same as Long acting
should be about 10-15% of Total daily dose, can be used Q1-6h PRN

25
Corticosteroids indicated for...
moderate to severe somatic and visceral pain as single agent or combo with agents used in bone pain
26
Bowel Regimen
should start stimulant laxative w/ opioids if no BM in 2+ days, titrate up stim laxative and can add osmotic inc fluid intake, exercise/mobility and fiber in diet
27
drugs for Dyspnea
usually opioids and that conc oral morphine give really small dose to patients
28
Pharm therapy for anxiety
1st line = SSRI/SNRI 2nd = Benzo 3rd = Adjunctives
29
Risk factors for depression in serious illness
Age = younger pts Prior history of depression Uncontrolled symptoms Type of illness
30
Gold standard for depression in serious illness
PHQ-9 > 10 = indicates likely major depression in general population in pts w/ serious illness, lower threshold (> 6) should be consideration of txm
31
symptoms clusters
when 3 or more concurrent symptoms are related to each other