lecture 10 Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis Flashcards
What are the 2 proposed pathways for initiating OA
micro fracturing of bone
Chondrocyte damage
What are 3 commonly affected joints in OA
- Cervical and lumbar spine
- 1at CMC joint
Distal phalange joint
Where are Heberden’s nodes found
distal interphalangeal (DIP) joints
What is the Class IV Functional Status of RA?
terminal- Limited in ability to perform usual self-care, vocational, and avocational activities.
Which stage of the Classification of Progression of RA might someone have bony ankylosis?
4th stage (terminal)
Ibuprofen and Vioxx are which class of drugs
COX-1 Inhibitors
Methotrexate is which class of drugs
COX-2 inhibitors
Which type of muscle contraction is recommended for somebody in a flare-up of RA?
Isometric contraction
RA is an autoimmune disease where the body attacks its own ___
collagen
Which condition best describes somebody with low back pain greater than 3 months and decreased chest/rib expansion
Ankylosing spondylus
What is one symptom of uveitis
Eye pain
What is the name of the protein receptor attached to the cell membrane of white blood cells and correlates with some autoimmune diseases
Toll-like receptor 4 (TLR4)
Reiter’s disease is thought to be caused by a _______ infection
bacterial infection (UTI, STI)
Which condition may see the person develop a “butterfly rash?
SLE (type of lupus)
What is the name of protein in gluten that is an amino acid chain not completely broken down in digestion
Gliadin
