Lecture 10; Arrythmias Flashcards
sawtooth pattern
atrial flutter
where does atrial flutter originate
cavo-tricuspid isthmus counterclockwise between IVC and tricuspid
treatment of atrial flutter
same as afib
- rate and anticoagulation
- most need to be ablated because they are hard to control with medicaitons
unstable atrial arrythmia tx
cardioversion
stable atrial arrhythmia
- vagal/ AV manuevers
- BB, diltiazem
goal HR in atrial fibrillation
HR < 80 at rest
HR < 110 with exercize
Medications for rate control in afib
BB (proponalol, metoprolol, esmolol)
non-hydropyradime (diltiazem, verapamil)
digoxin
amioadorane
AV blockers (allow the conduction from the atrium to be conducted to the ventricle
Amiodarone toxicity
What A BITCH
B: bradycardia, Blue man sydnrome
I: interstitial lung disease, increased QTC
T: thyrdoid
C: - corneal micro
- cytochrome P450
- Increase Warfarin/Simvitastatin/digoxin levels - needs dose reduction
H: Hepatic, Hypotension
which rhythm control is used if structural heart disease
amiodarone
which rhythm control if no structural heart disease
flecanide
dofetilide
propafenone
ibutilide
lone a fib tx
nothing or ASA
CHADS2VASC 0-1
valvular afib tx
wafarin
tx non-valvular afib
CHA2DS2-VASc
Condition Points
C Congestive heart failure (or Left ventricular systolic dysfunction) 1
H Hypertension: blood pressure consistently above 140/90 mmHg (or treated hypertension on medication) 1
A2 Age ≥75 years 2
D Diabetes Mellitus 1
S2 Prior Stroke or TIA or thromboembolism 2
V Vascular disease (e.g. peripheral artery disease, myocardial infarction, aortic plaque) 1
A Age 65–74 years 1
Sc Sex category (i.e. female sex) 1
HAS BLED
> 3
caution
Condition Points
H Hypertension: (uncontrolled, >160 mmHg systolic) 1
A Abnormal renal function: Dialysis, transplant, Cr >2.26 mg/dL or >200 µmol/L ==> 1
Abnormal liver function: Cirrhosis or Bilirubin >2x Normal or AST/ALT/AP >3x Normal 1
S Stroke: Prior history of stroke 1
B Bleeding: Prior Major Bleeding or Predisposition to Bleeding 1
L Labile INR: (Unstable/high INR), Time in Therapeutic Range 65 years
1
D Prior Alcohol or Drug Usage History (≥ 8 drinks/week) == >1
Medication Usage Predisposing to Bleeding: (Antiplatelet agents, NSAIDs)
1
goal for INR afib
2-3
direct thrombin inhibitor
2 things to remember
digatraban
- renally adjusted
- no bridge needed
RAEF
rivoraxaban
Apixiban
Endoxaban
Factor XA inhibitors
which NOAC can be used in dialysis patients
apixiban - acting up kidneys
timing of anticoagulation around cardioversion
If cardioversion is planned, anticoagulation therapy is based on the duration of atrial fibrillation. For patients who are known to have been in atrial fibrillation for less than 48 hours, preprocedural anticoagulation is not necessary as the risk of thrombus formation is low. Patients with atrial fibrillation of unclear duration or those with atrial fibrillation for more than 48 hours require preprocedural anticoagulation. These patients should receive 3 weeks of therapeutic anticoagulation prior to cardioversion. Alternatively, transesophageal echocardiography (TEE) can be performed to look for an intracardiac thrombus. If TEE is negative for thrombus, acute cardioversion can be performed immediately
minimum of 4 weeks owing to an increased risk of thromboembolic events after restoration of sinus rhythm.
CAD + afib triple therapy management
if < 12 mo + stent ==> triple therapy
if < 12 mo, no stent = ASA + anticoagulation
if > 12 mo –> anticoagulation only
what are the contraindictations to ablation
- cannot be anticoagulated
wpw with afib
procainamide
best med post op afib
sotolal
when are PVC required to be treat
symtomatic/frequent (> 10,000 in 24 hours)
(>10% of all beat